| Entry |
|
|---|
| Name |
Clindamycin (USAN/INN);
Cleocin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C18H33ClN2O5S
|
|---|
| Exact mass |
424.1799
|
|---|
| Mol weight |
424.98
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01578 Lincosamide antibiotic
|
|---|
| Remark |
| Product (DG00435): | D00277<US> D01073<JP/US> D01990<US> D02132<JP/US> |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Comment |
Semisynthetic lincosamide
|
|---|
| Target |
50S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF01 Clindamycin
D00277 Clindamycin (USAN/INN) <US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA10 Clindamycin
D00277 Clindamycin (USAN/INN) <US>
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
J01FF Lincosamides
J01FF01 Clindamycin
D00277 Clindamycin (USAN/INN) <US>
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
D00277 Clindamycin
Drug classes [BR:br08332]
Antibacterial
DG01578 Lincosamide antibiotic
D00277 Clindamycin
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
D00277 Clindamycin (USAN/INN) <US>
Prodrugs [br08324.html]
D00277
Drug groups [BR:br08330]
Antibacterial
DG01578 Lincosamide antibiotic
DG00435 Clindamycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Lincosamide
DG00435 Clindamycin
Prodrugs [br08324.html]
DG00435
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 27
1 C1y C 21.5407 -15.6792
2 C1y C 21.5407 -17.0811
3 C1y C 22.7557 -17.7820
4 C1y C 23.9707 -17.0811
5 C1y C 23.9707 -15.6792
6 O2x O 22.7557 -14.9783
7 S2a S 25.1856 -14.9783
8 C1a C 25.1856 -13.5765
9 O1a O 25.1856 -17.7820
10 O1a O 22.7557 -19.1840
11 O1a O 20.3258 -17.7820
12 C1c C 20.3258 -14.9783
13 N1b N 19.1108 -15.6792
14 C1c C 20.3258 -13.5765
15 X Cl 19.1108 -12.8755
16 C1a C 21.5407 -12.8755
17 C5a C 17.8959 -14.9783
18 C1y C 16.6809 -15.6792
19 O5a O 17.8959 -13.5765
20 N1y N 15.5547 -14.8842
21 C1x C 14.4353 -15.7071
22 C1y C 14.8822 -17.0367
23 C1x C 16.2661 -17.0298
24 C1a C 15.5547 -13.4842
25 C1b C 14.1883 -18.2527
26 C1b C 12.8102 -18.2598
27 C1a C 12.1121 -19.4837
BOND 28
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 5 7 1 #Down
8 7 8 1
9 4 9 1 #Down
10 3 10 1 #Up
11 2 11 1 #Up
12 1 12 1
13 12 13 1
14 12 14 1
15 14 15 1 #Up
16 14 16 1
17 13 17 1
18 18 17 1 #Down
19 17 19 2
20 18 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 18 23 1
25 20 24 1
26 22 25 1 #Up
27 25 26 1
28 26 27 1
|
|---|
