| Entry |
|
|---|
| Name |
Latanoprost (JAN/USP/INN);
Xalatan (TN) |
|---|
| Product |
|
|---|
| Generic |
LATANOPROST (A-S Medication Solutions), LATANOPROST (A-S Medication Solutions), LATANOPROST (Aurobindo Pharma Limited), LATANOPROST (Bausch & Lomb Incorporated), LATANOPROST (GLENMARK PHARMACEUTICALS), LATANOPROST (Gland Pharma Limited), LATANOPROST (Mylan Pharmaceuticals), LATANOPROST (Proficient Rx LP), LATANOPROST (Rising Pharma Holdings), LATANOPROST (Sagent Pharmaceuticals), LATANOPROST (Sandoz), LATANOPROST (Somerset Therapeutics) |
|---|
| Formula |
C26H40O5
|
|---|
| Exact mass |
432.2876
|
|---|
| Mol weight |
432.59
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Therapeutic category: | 1319 |
| Product (mixture): | D07505<JP> D10804<JP> D11558<US> |
|
|---|
| Efficacy |
Antiglaucoma, Prostaglandin F receptor agonist |
|---|
| Disease |
Open-angle glaucoma [DS: H00612] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EE Prostaglandin analogues
S01EE01 Latanoprost
D00356 Latanoprost (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Prostaglandin and Prostamide Analogs, Ophthalmic
Latanoprost
D00356 Latanoprost (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00356 Latanoprost (JAN/USP/INN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
D00356 Latanoprost
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00356 Latanoprost
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00356 Latanoprost
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGFR
D00356 Latanoprost (JAN/USP/INN) <JP/US>
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 31
1 C1y C 18.8346 -20.3048
2 C1y C 18.8346 -21.7052
3 C1y C 17.4343 -19.8847
4 C1b C 20.0249 -19.6046
5 C1y C 17.5043 -22.1253
6 C1b C 20.0249 -22.4054
7 C1x C 16.6641 -21.0050
8 C2b C 21.2152 -20.3048
9 O1a O 17.0842 -23.5256
10 C1b C 21.2152 -21.7052
11 C1c C 22.4755 -22.4054
12 C1b C 23.6658 -21.7052
13 O1a O 22.4755 -23.8057
14 C1b C 24.9261 -22.4054
15 C8y C 24.9261 -23.8057
16 C8x C 26.1164 -24.5059
17 C8x C 26.1164 -25.9061
18 C8x C 24.9261 -26.6063
19 C8x C 23.6658 -25.9061
20 C8x C 23.6658 -24.5059
21 O1a O 16.9442 -18.5544
22 C2b C 22.6156 -20.3048
23 C1b C 23.8059 -19.6046
24 C1b C 24.9961 -20.3048
25 C1b C 26.1864 -19.6046
26 C7a C 27.3767 -20.3048
27 O7a O 28.5670 -19.6046
28 C1c C 29.7573 -20.3048
29 C1a C 30.9476 -19.6046
30 O6a O 27.3767 -21.7052
31 C1a C 29.7573 -21.7052
BOND 32
1 12 14 1
2 5 7 1
3 14 15 1
4 1 2 1
5 1 3 1
6 1 4 1 #Down
7 2 5 1
8 2 6 1 #Up
9 15 16 2
10 16 17 1
11 17 18 2
12 18 19 1
13 19 20 2
14 20 15 1
15 3 7 1
16 4 8 1
17 5 9 1 #Down
18 6 10 1
19 10 11 1
20 11 12 1
21 11 13 1 #Down
22 3 21 1 #Down
23 8 22 2
24 23 24 1
25 23 22 1
26 24 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 28 29 1
31 26 30 2
32 28 31 1
|
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