| Entry |
|
|---|
| Name |
Latanoprost (JAN/USP/INN);
Xalatan (TN) |
|---|
| Product |
|
|---|
| Generic |
LATANOPROST (A-S Medication Solutions), LATANOPROST (A-S Medication Solutions), LATANOPROST (Aurobindo Pharma Limited), LATANOPROST (Bausch & Lomb Incorporated), LATANOPROST (GLENMARK PHARMACEUTICALS), LATANOPROST (Gland Pharma Limited), LATANOPROST (Mylan Pharmaceuticals), LATANOPROST (NuCare Pharmaceuticals), LATANOPROST (Proficient Rx LP), LATANOPROST (Rising Pharma Holdings), LATANOPROST (Sagent Pharmaceuticals), LATANOPROST (Sandoz), LATANOPROST (Somerset Therapeutics) |
|---|
| Formula |
C26H40O5
|
|---|
| Exact mass |
432.2876
|
|---|
| Mol weight |
432.59
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Therapeutic category: | 1319 |
| Product (mixture): | D07505<JP> D10804<JP> D11558<US> |
|
|---|
| Efficacy |
Antiglaucoma, Prostaglandin F receptor agonist |
|---|
| Disease |
Open-angle glaucoma [DS: H00612] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EE Prostaglandin analogues
S01EE01 Latanoprost
D00356 Latanoprost (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Prostaglandin and Prostamide Analogs, Ophthalmic
Latanoprost
D00356 Latanoprost (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00356 Latanoprost (JAN/USP/INN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
D00356 Latanoprost
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00356 Latanoprost
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00356 Latanoprost
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGFR
D00356 Latanoprost (JAN/USP/INN) <JP/US>
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 31
1 C1y C 18.8346 -20.3048
2 C1y C 18.8346 -21.7052
3 C1y C 17.4343 -19.8847
4 C1b C 20.0249 -19.6046
5 C1y C 17.5043 -22.1253
6 C1b C 20.0249 -22.4054
7 C1x C 16.6641 -21.0050
8 C2b C 21.2152 -20.3048
9 O1a O 17.0842 -23.5256
10 C1b C 21.2152 -21.7052
11 C1c C 22.4755 -22.4054
12 C1b C 23.6658 -21.7052
13 O1a O 22.4755 -23.8057
14 C1b C 24.9261 -22.4054
15 C8y C 24.9261 -23.8057
16 C8x C 26.1164 -24.5059
17 C8x C 26.1164 -25.9061
18 C8x C 24.9261 -26.6063
19 C8x C 23.6658 -25.9061
20 C8x C 23.6658 -24.5059
21 O1a O 16.9442 -18.5544
22 C2b C 22.6156 -20.3048
23 C1b C 23.8059 -19.6046
24 C1b C 24.9961 -20.3048
25 C1b C 26.1864 -19.6046
26 C7a C 27.3767 -20.3048
27 O7a O 28.5670 -19.6046
28 C1c C 29.7573 -20.3048
29 C1a C 30.9476 -19.6046
30 O6a O 27.3767 -21.7052
31 C1a C 29.7573 -21.7052
BOND 32
1 12 14 1
2 5 7 1
3 14 15 1
4 1 2 1
5 1 3 1
6 1 4 1 #Down
7 2 5 1
8 2 6 1 #Up
9 15 16 2
10 16 17 1
11 17 18 2
12 18 19 1
13 19 20 2
14 20 15 1
15 3 7 1
16 4 8 1
17 5 9 1 #Down
18 6 10 1
19 10 11 1
20 11 12 1
21 11 13 1 #Down
22 3 21 1 #Down
23 8 22 2
24 23 24 1
25 23 22 1
26 24 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 28 29 1
31 26 30 2
32 28 31 1
|
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