KEGG   DRUG: PraziquantelHelp
Entry
D00471                      Drug                                   

Name
Praziquantel (JAN/USP/INN);
Biltricide (TN)
Product
  Generic
Formula
C19H24N2O2
Exact mass
312.1838
Mol weight
312.4061
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Enzyme substrate
 DG01633  CYP3A substrate
Remark
Same as: C07367
Therapeutic category: 6429
ATC code: P02BA01
Product: D00471<JP/US>
Efficacy
Anthelmintic (veterinary)
  Disease
Infections due to schistosoma [DS:H01045]
Infections due to liver flukes [DS:H01610 H01617 H01628]
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P02 ANTHELMINTICS
   P02B ANTITREMATODALS
    P02BA Quinoline derivatives and related substances
     P02BA01 Praziquantel
      D00471  Praziquantel (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Antiparasitics
  Anthelmintics
   Praziquantel
    D00471  Praziquantel (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  64  Parasitics (systemic)
   642  Anthelmintics
    6429  Others
     D00471  Praziquantel (JAN/USP/INN)
Antiinfectives [br08350.html]
 Antiparasitics
  D00471
BRITE hierarchy
Other DBs
CAS: 55268-74-1
PubChem: 7847537
ChEMBL: CHEMBL976
DrugBank: DB01058
LigandBox: D00471
NIKKAJI: J2.787A
LinkDB All DBs
KCF data Show

ATOM        23
            1   C8x C     7.9800  -18.8300
            2   C8x C     7.9800  -20.2300
            3   C8x C     9.1924  -20.9300
            4   C8y C    10.4049  -20.2300
            5   C8y C    10.4049  -18.8300
            6   C8x C     9.1924  -18.1300
            7   C1x C    11.6173  -20.9300
            8   C1x C    12.8297  -20.2300
            9   N1y N    12.8297  -18.8300
            10  C1y C    11.6173  -18.1300
            11  C5x C    14.0422  -18.1300
            12  C1x C    14.0422  -16.7300
            13  N1y N    12.8297  -16.0300
            14  C1x C    11.6173  -16.7300
            15  C5a C    12.8297  -14.6301
            16  O5a O    11.6025  -13.9215
            17  C1y C    14.0274  -13.9386
            18  O5x O    15.2753  -18.8422
            19  C1x C    15.2155  -14.6247
            20  C1x C    16.4280  -13.9247
            21  C1x C    16.4280  -12.5247
            22  C1x C    15.2399  -11.8387
            23  C1x C    14.0274  -12.5386
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   13  15 1
            18   15  16 2
            19   15  17 1
            20   11  18 2
            21   17  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 1
            25   22  23 1
            26   17  23 1

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