| Entry |
|
|---|
| Name |
Praziquantel (JAN/USP/INN);
Biltricide (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C19H24N2O2
|
|---|
| Exact mass |
312.1838
|
|---|
| Mol weight |
312.41
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Therapeutic category: | 6429 |
|
|---|
| Efficacy |
Anthelmintic (veterinary) |
|---|
| Disease |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P02 ANTHELMINTICS
P02B ANTITREMATODALS
P02BA Quinoline derivatives and related substances
P02BA01 Praziquantel
D00471 Praziquantel (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antiparasitics
Anthelmintics
Praziquantel
D00471 Praziquantel (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
64 Parasitics (systemic)
642 Anthelmintics
6429 Others
D00471 Praziquantel (JAN/USP/INN)
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D00471 Praziquantel
Antimicrobials [BR:br08307]
Antiparasitics
Antitrematodal agents
Quinoline derivatives and related substances
D00471 Praziquantel (JAN/USP/INN) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00471
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C8x C 7.9800 -18.8300
2 C8x C 7.9800 -20.2300
3 C8x C 9.1924 -20.9300
4 C8y C 10.4049 -20.2300
5 C8y C 10.4049 -18.8300
6 C8x C 9.1924 -18.1300
7 C1x C 11.6173 -20.9300
8 C1x C 12.8297 -20.2300
9 N1y N 12.8297 -18.8300
10 C1y C 11.6173 -18.1300
11 C5x C 14.0422 -18.1300
12 C1x C 14.0422 -16.7300
13 N1y N 12.8297 -16.0300
14 C1x C 11.6173 -16.7300
15 C5a C 12.8297 -14.6301
16 O5a O 11.6025 -13.9215
17 C1y C 14.0274 -13.9386
18 O5x O 15.2753 -18.8422
19 C1x C 15.2155 -14.6247
20 C1x C 16.4280 -13.9247
21 C1x C 16.4280 -12.5247
22 C1x C 15.2399 -11.8387
23 C1x C 14.0274 -12.5386
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 13 15 1
18 15 16 2
19 15 17 1
20 11 18 2
21 17 19 1
22 19 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 17 23 1
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