KEGG   DRUG: AmobarbitalHelp
Entry
D00555                      Drug                                   

Name
Amobarbital (JP17/INN);
Isomytal (TN)
Formula
C11H18N2O3
Exact mass
226.1317
Mol weight
226.2722
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01837  Barbiturate sedative-hypnotics
 DG01567  GABA-A receptor agonist
Enzyme inducer
 DG02853  CYP3A inducer
Remark
Same as: C07536
Therapeutic category: 1125
ATC code: N05CA02
Chemical structure group: DG00916
Product (DG00916): D00555<JP>
Efficacy
Sedative-hypnotic
Comment
Barbiturates
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
CYP induction: CYP3A [HSA:1576 1577 1551]
Drug interaction
Structure map
map07032  Hypnotics
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CA Barbiturates, plain
     N05CA02 Amobarbital
      D00555  Amobarbital (JP17/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1125  Barbiturates and thiobarbiturates
     D00555  Amobarbital (JP17/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00555  Amobarbital (JP17/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00555  Amobarbital
Drug classes of therapeutic agents [br08360.html]
 Psychiatric agents
  D00555
BRITE hierarchy
Other DBs
CAS: 57-43-2
PubChem: 7847621
ChEBI: 2673
ChEMBL: CHEMBL267894
DrugBank: DB01351
LigandBox: D00555
NIKKAJI: J1.381A
LinkDB All DBs
KCF data Show

ATOM        16
            1   C1z C    20.9187  -17.4474
            2   C5x C    20.9187  -18.8579
            3   C5x C    19.7006  -16.7423
            4   C1b C    22.4050  -17.4533
            5   C1b C    20.9071  -16.0952
            6   N1x N    19.7006  -19.5633
            7   O5x O    22.1311  -19.5633
            8   N2x N    18.4767  -17.4474
            9   O5x O    19.7006  -15.3377
            10  C1b C    23.1103  -16.4509
            11  C1a C    22.1195  -15.3841
            12  C2y C    18.4767  -18.8579
            13  C1c C    24.5440  -16.4566
            14  O1a O    17.2525  -19.5633
            15  C1a C    25.2493  -17.6748
            16  C1a C    25.2493  -15.2385
BOND        16
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 2
            7     3   8 1
            8     3   9 2
            9     4  10 1
            10    5  11 1
            11    6  12 1
            12   10  13 1
            13   12  14 1
            14   13  15 1
            15   13  16 1
            16    8  12 2

» Japanese version   » Back

DBGET integrated database retrieval system