KEGG   DRUG: Methazolamide
Entry
D00655                      Drug                                   

Name
Methazolamide (JAN/USP/INN);
Neptazane (TN)
Product
  Generic
Formula
C5H8N4O3S2
Exact mass
236.0038
Mol weight
236.272
Structure
Simcomp
Class
Cardiovascular agent
 DG01534  Carbonic anhydrase inhibitor
Ophthalmic agent
 DG03201  Intraocular pressure lowering agent
Remark
Same as: C07764
ATC code: S01EC05
Product: D00655<US>
Efficacy
Antiglaucoma, Carbonic anhydrase inhibitor
  Disease
Open-angle glaucoma [DS:H00612]
Target
  Pathway
hsa04964  Proximal tubule bicarbonate reclamation
Interaction
Structure map
map07017  Sulfonamide derivatives - diuretics
map07054  Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EC Carbonic anhydrase inhibitors
     S01EC05 Methazolamide
      D00655  Methazolamide (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
 Ophthalmic Agents
  Intraocular Pressure Lowering Agents
   Carbonic Anhydrase Inhibitors, Ophthalmic
    Methazolamide
     D00655  Methazolamide (JAN/USP/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01534  Carbonic anhydrase inhibitor
   D00655  Methazolamide
 Ophthalmic agent
  DG03201  Intraocular pressure lowering agent
   D00655  Methazolamide
Drug classes [BR:br08332]
 Ophthalmic agent
  DG03201  Intraocular pressure lowering agent
   D00655  Methazolamide
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases (EC4)
   Aldehyde-lyases
    CA
     D00655  Methazolamide (JAN/USP/INN) <US>
Other DBs
CAS: 554-57-4
PubChem: 7847721
ChEBI: 6822
ChEMBL: CHEMBL19
DrugBank: DB00703
LigandBox: D00655
NIKKAJI: J2.070B
LinkDB
KCF data

ATOM        14
            1   C8y C    26.4566  -18.5315
            2   S2x S    25.3215  -17.7066
            3   N4y N    26.0236  -19.8597
            4   N2b N    27.6618  -17.8177
            5   C8y C    24.1866  -18.5315
            6   N5x N    24.6254  -19.8597
            7   C1a C    26.8486  -20.9889
            8   C5a C    28.8729  -18.5198
            9   S4a S    22.7882  -18.5258
            10  C1a C    30.0841  -17.8120
            11  O5a O    28.8729  -19.9183
            12  N1a N    22.8465  -19.9240
            13  O3c O    22.8465  -17.1273
            14  O3c O    21.3840  -18.5258
BOND        14
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     8  10 1
            10    8  11 2
            11    9  12 1
            12    9  13 2
            13    9  14 2
            14    5   6 2

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