| Entry |
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| Name |
Trichlormethiazide (JP18/USP/INN);
Naqua (TN) |
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| Formula |
C8H8Cl3N3O4S2
|
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| Exact mass |
378.9022
|
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| Mol weight |
380.66
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
| Therapeutic category: | 2132 |
| Product (mixture): | D10480<JP> |
|
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| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
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| Comment |
Thiazides
|
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| Target |
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| Interaction |
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| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA06 Trichlormethiazide
D00658 Trichlormethiazide (JP18/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2132 Thiazides
D00658 Trichlormethiazide (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D00658 Trichlormethiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D00658 Trichlormethiazide
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00658 Trichlormethiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D00658 Trichlormethiazide (JP18/USP/INN) <JP>
SLC12A3 (TSC)
D00658 Trichlormethiazide (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00658 Trichlormethiazide
D00658 Trichlormethiazide tablets
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 20
1 C8y C 24.9600 -17.0201
2 C8y C 25.0243 -18.4245
3 C8x C 26.1773 -16.3296
4 S2x S 23.7547 -16.3238
5 N1x N 23.7547 -19.1210
6 C8x C 26.1656 -19.1267
7 C8y C 27.3827 -17.0318
8 N1x N 22.5374 -17.0201
9 O3c O 22.5316 -15.6216
10 O3c O 24.9543 -15.6158
11 C1y C 22.5374 -18.4245
12 C8y C 27.3769 -18.4305
13 S4a S 28.5823 -16.3296
14 C1c C 21.3203 -19.1210
15 X Cl 28.5765 -19.1267
16 N1a N 29.7936 -15.4811
17 O3c O 27.5933 -15.3290
18 O3c O 29.6356 -17.1781
19 X Cl 20.1090 -18.4245
20 X Cl 21.3844 -20.5195
BOND 21
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 4 9 2
9 4 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 2
17 13 18 2
18 14 19 1
19 14 20 1
20 7 12 1
21 8 11 1
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