Entry |
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Name |
Mometasone furoate (JAN/USP); Asmanex (TN); Elocon (TN) |
Product |
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Generic |
MOMETASONE FUROATE (A-S Medication Solutions), MOMETASONE FUROATE (A-S Medication Solutions), MOMETASONE FUROATE (Amneal Pharmaceuticals LLC), MOMETASONE FUROATE (Apotex Corp.), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Bryant Ranch Prepack), MOMETASONE FUROATE (Cosette Pharmaceuticals), MOMETASONE FUROATE (Cosette Pharmaceuticals), MOMETASONE FUROATE (Glenmark Pharmaceuticals), MOMETASONE FUROATE (Glenmark Pharmaceuticals), MOMETASONE FUROATE (Glenmark Pharmaceuticals), MOMETASONE FUROATE (Golden State Medical Supply), MOMETASONE FUROATE (Padagis Israel Pharmaceuticals), MOMETASONE FUROATE (Padagis Israel Pharmaceuticals), MOMETASONE FUROATE (Padagis Israel Pharmaceuticals), MOMETASONE FUROATE (Preferred Pharmaceuticals), MOMETASONE FUROATE (Preferred Pharmaceuticals), MOMETASONE FUROATE (Preferred Pharmaceuticals), MOMETASONE FUROATE (Proficient Rx LP), MOMETASONE FUROATE (Proficient Rx LP), MOMETASONE FUROATE (Proficient Rx LP), MOMETASONE FUROATE (RPK Pharmaceuticals), MOMETASONE FUROATE (RPK Pharmaceuticals), MOMETASONE FUROATE (Taro Pharmaceuticals U.S.A.), MOMETASONE FUROATE (Taro Pharmaceuticals U.S.A.), MOMETASONE FUROATE (Taro Pharmaceuticals U.S.A.) |
Formula |
C27H30Cl2O6
|
Exact mass |
520.1419
|
Mol weight |
521.42
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Structure |
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Simcomp |
|
Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
Remark |
Product (DG00419): | D00690<JP/US> D03325<JP/US> |
Product (mixture): | D10295<US> D11861<JP> D11862<JP> D12501<US> |
|
Efficacy |
Antiasthmatic, Anti-inflammatory, Glucocorticoid receptor agonist |
Disease |
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
Interaction |
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Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC13 Mometasone
D00690 Mometasone furoate (JAN/USP) <JP/US>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XC Corticosteroids, potent, other combinations
D07XC03 Mometasone
D00690 Mometasone furoate (JAN/USP) <JP/US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD09 Mometasone
D00690 Mometasone furoate (JAN/USP) <JP/US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA07 Mometasone
D00690 Mometasone furoate (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, Medium Potency
Mometasone
D00690 Mometasone furoate (JAN/USP)
Respiratory Tract/Pulmonary Agents
Anti-inflammatories, Inhaled Corticosteroids
Mometasone
D00690 Mometasone furoate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
229 Miscellaneous
2290 Miscellaneous
D00690 Mometasone furoate (JAN/USP)
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D00690 Mometasone furoate (JAN/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00419 Mometasone
D00690 Mometasone furoate
Dermatological agent
DG03243 Atopic dermatitis agent
D00690 Mometasone furoate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00419 Mometasone
D00690 Mometasone furoate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00690 Mometasone furoate
Dermatological agent
DG03243 Atopic dermatitis agent
D00690 Mometasone furoate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00690 Mometasone furoate (JAN/USP) <JP/US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00690
Topical steroids potency [br08317.html]
Classification in the USA
D00690
Classification in Japan
D00690
Rx-to-OTC switch list in the USA [br08315.html]
D00690
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00419 Mometasone
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00419 Mometasone
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Other DBs |
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LinkDB |
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KCF data |
ATOM 35
1 C1z C 33.4094 -17.0168
2 C1z C 32.2455 -17.6911
3 C1y C 34.5745 -17.6967
4 O7a O 35.2692 -15.9227
5 C5a C 33.3979 -15.6626
6 C1y C 32.2455 -19.0336
7 C1x C 31.0814 -17.0111
8 C1a C 32.2396 -16.3195
9 C1x C 34.5676 -19.0395
10 C1a C 35.8931 -18.0539
11 C7a C 36.6407 -15.9227
12 C1b C 34.5851 -14.9768
13 O5a O 32.2109 -14.9883
14 C1y C 31.0758 -19.7079
15 C1y C 29.9116 -17.6852
16 C8y C 37.3207 -14.7357
17 O6a O 37.3207 -17.1098
18 X Cl 34.5736 -13.6053
19 C1z C 29.9060 -19.0336
20 C1x C 31.0814 -21.0563
21 O1a O 28.7362 -16.9995
22 C8x C 38.6969 -14.7425
23 O2x O 36.9040 -13.4470
24 C1z C 28.7418 -19.7079
25 X Cl 29.9001 -20.3763
26 C1x C 29.9116 -21.7363
27 C8x C 39.1183 -13.4369
28 C8x C 38.0098 -12.6305
29 C2y C 28.7418 -21.0620
30 C2x C 27.5721 -19.0336
31 C1a C 28.7303 -18.3595
32 C2x C 27.5721 -21.7363
33 C2x C 26.4023 -19.7079
34 C5x C 26.4023 -21.0620
35 O5x O 25.2268 -21.7305
BOND 39
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 3 10 1 #Down
10 4 11 1
11 5 12 1
12 5 13 2
13 6 14 1
14 7 15 1
15 11 16 1
16 11 17 2
17 12 18 1
18 14 19 1
19 14 20 1
20 15 21 1 #Up
21 16 22 2
22 16 23 1
23 19 24 1
24 19 25 1 #Down
25 20 26 1
26 22 27 1
27 23 28 1
28 24 29 1
29 24 30 1
30 24 31 1 #Up
31 29 32 2
32 30 33 2
33 32 34 1
34 34 35 2
35 6 9 1
36 15 19 1
37 26 29 1
38 27 28 2
39 33 34 1
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