KEGG   DRUG: Clorazepate dipotassium
Entry
D00694                      Drug                                   
Name
Clorazepate dipotassium (JP18/USP);
Tranxene (TN)
Product
  Generic
Formula
C16H10ClN2O3. KOH. K
Exact mass
407.9681
Mol weight
408.92
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01914  Anxiolytics, benzodiazepine derivatives
Remark
Therapeutic category: 1124
ATC code: N05BA05
Chemical structure group: DG01218
Product (DG01218): D00694<JP/US>
Efficacy
Antianxiety, Minor tranquilizer
  Disease
Anxiety disorders [DS:H01662]
Comment
Benzodiazepine derivative
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Structure map
map07030  Anxiolytics
map07230  GABA-A receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA05 Potassium clorazepate
      D00694  Clorazepate dipotassium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Benzodiazepines
    Clorazepate
     D00694  Clorazepate dipotassium (JP18/USP)
 Anxiolytics
  Benzodiazepines
   Clorazepate
    D00694  Clorazepate dipotassium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D00694  Clorazepate dipotassium (JP18/USP)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01914  Anxiolytics, benzodiazepine derivatives
   DG01218  Clorazepic acid
    D00694  Clorazepate dipotassium
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D00694  Clorazepate dipotassium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00694  Clorazepate dipotassium
  D00694  Clorazepate dipotassium capsules
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01914  Anxiolytics, benzodiazepine derivatives
   DG01218  Clorazepic acid
Other DBs
CAS: 57109-90-7
PubChem: 7847759
ChEBI: 3762
LigandBox: D00694
NIKKAJI: J252.840A
LinkDB
KCF data

ATOM        25
            1   C2y C    24.3534  -14.2894
            2   C8y C    23.5113  -13.1798
            3   C8y C    23.8465  -11.8230
            4   N1x N    25.1075  -11.2449
            5   N2x N    25.7592  -14.3146
            6   C5x C    26.3611  -11.8672
            7   C1y C    26.6476  -13.2359
            8   C8x C    22.8394  -10.8546
            9   C8x C    21.4974  -11.2427
            10  C8y C    21.1622  -12.5995
            11  C8x C    22.1693  -13.5676
            12  X   Cl   19.7974  -12.9939
            13  C8y C    23.7189  -15.5391
            14  C8x C    22.3173  -15.5391
            15  C8x C    21.6173  -16.7516
            16  C8x C    22.3173  -17.9640
            17  C8x C    23.7189  -17.9640
            18  C8x C    24.4189  -16.7516
            19  C6a C    27.8601  -13.9359
            20  O6a O    29.0725  -13.2359 #-
            21  O5x O    27.4703  -11.0095
            22  O6a O    27.8601  -15.3300
            23  Z   K    30.5200  -13.3000 #+
            24  Z   K    27.5100  -17.3600
            25  O1a O    28.9100  -17.3600
BOND        25
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13   10  12 1
            14    1  13 1
            15   13  14 1
            16   14  15 2
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   13  18 2
            21    7  19 1
            22   19  20 1
            23    6  21 2
            24   19  22 2
            25   24  25 1

» Japanese version   » Back

DBGET integrated database retrieval system