Entry |
|
Name |
Clorazepate dipotassium (JP18/USP); Tranxene (TN) |
Product |
|
Generic |
|
Formula |
C16H10ClN2O3. KOH. K
|
Exact mass |
407.9681
|
Mol weight |
408.92
|
Structure |
|
Simcomp |
|
Class |
Neuropsychiatric agent
DG01914 Anxiolytics, benzodiazepine derivatives
|
Remark |
Therapeutic category: | 1124 |
Product (DG01218): | D00694<JP/US> |
|
Efficacy |
Antianxiety, Minor tranquilizer |
Disease |
|
Comment |
Benzodiazepine derivative
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Structure map |
map07230 | GABA-A receptor agonists/antagonists |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BA Benzodiazepine derivatives
N05BA05 Potassium clorazepate
D00694 Clorazepate dipotassium (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
Gamma-aminobutyric Acid (GABA) Augmenting Agents
Benzodiazepines
Clorazepate
D00694 Clorazepate dipotassium (JP18/USP)
Anxiolytics
Benzodiazepines
Clorazepate
D00694 Clorazepate dipotassium (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D00694 Clorazepate dipotassium (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01914 Anxiolytics, benzodiazepine derivatives
DG01218 Clorazepic acid
D00694 Clorazepate dipotassium
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00694 Clorazepate dipotassium (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00694 Clorazepate dipotassium
D00694 Clorazepate dipotassium capsules
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01914 Anxiolytics, benzodiazepine derivatives
DG01218 Clorazepic acid
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 25
1 C2y C 24.3534 -14.2894
2 C8y C 23.5113 -13.1798
3 C8y C 23.8465 -11.8230
4 N1x N 25.1075 -11.2449
5 N2x N 25.7592 -14.3146
6 C5x C 26.3611 -11.8672
7 C1y C 26.6476 -13.2359
8 C8x C 22.8394 -10.8546
9 C8x C 21.4974 -11.2427
10 C8y C 21.1622 -12.5995
11 C8x C 22.1693 -13.5676
12 X Cl 19.7974 -12.9939
13 C8y C 23.7189 -15.5391
14 C8x C 22.3173 -15.5391
15 C8x C 21.6173 -16.7516
16 C8x C 22.3173 -17.9640
17 C8x C 23.7189 -17.9640
18 C8x C 24.4189 -16.7516
19 C6a C 27.8601 -13.9359
20 O6a O 29.0725 -13.2359 #-
21 O5x O 27.4703 -11.0095
22 O6a O 27.8601 -15.3300
23 Z K 30.5200 -13.3000 #+
24 Z K 27.5100 -17.3600
25 O1a O 28.9100 -17.3600
BOND 25
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 10 12 1
14 1 13 1
15 13 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 13 18 2
21 7 19 1
22 19 20 1
23 6 21 2
24 19 22 2
25 24 25 1
|