| Entry |
|
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| Name |
Orphenadrine citrate (USP);
Norflex (TN) |
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| Product |
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| Generic |
ORPHENADRINE CITRATE (A-S Medication Solutions), ORPHENADRINE CITRATE (Actavis Pharma), ORPHENADRINE CITRATE (Advanced Rx Pharmacy of Tennessee), ORPHENADRINE CITRATE (Advanced Rx Pharmacy of Tennessee), ORPHENADRINE CITRATE (Bryant Ranch Prepack), ORPHENADRINE CITRATE (Bryant Ranch Prepack), ORPHENADRINE CITRATE (Direct_Rx), ORPHENADRINE CITRATE (Hikma Pharmaceuticals USA), ORPHENADRINE CITRATE (Lake Erie Medical DBA Quality Care Products LLC), ORPHENADRINE CITRATE (Lupin Pharmaceuticals), ORPHENADRINE CITRATE (Northwind Pharmaceuticals), ORPHENADRINE CITRATE (NuCare Pharmaceuticals), ORPHENADRINE CITRATE (PD-Rx Pharmaceuticals), ORPHENADRINE CITRATE (Preferred Pharmaceuticals), ORPHENADRINE CITRATE (Proficient Rx LP), ORPHENADRINE CITRATE (Proficient Rx LP), ORPHENADRINE CITRATE (REMEDYREPACK), ORPHENADRINE CITRATE (RedPharm Drug), ORPHENADRINE CITRATE (RedPharm Drug), ORPHENADRINE CITRATE (Sagent Pharmaceuticals), ORPHENADRINE CITRATE (Sandoz), ORPHENADRINE CITRATE (St. Mary's Medical Park Pharmacy) |
|---|
| Formula |
C18H23NO. C6H8O7
|
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| Exact mass |
461.2050
|
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| Mol weight |
461.50
|
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
|
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| Remark |
| Product (DG01252): | D00774<US> |
| Product (mixture): | D11849<US> |
|
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| Efficacy |
Skeletal muscle relaxant |
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03B MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
M03BC Ethers, chemically close to antihistamines
M03BC01 Orphenadrine (citrate)
D00774 Orphenadrine citrate (USP) <US>
USP drug classification [BR:br08302]
Skeletal Muscle Relaxants
Orphenadrine
D00774 Orphenadrine citrate (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
D00774 Orphenadrine citrate
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
D00774 Orphenadrine citrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D00774 Orphenadrine citrate (USP) <US>
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D00774 Orphenadrine citrate (USP) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG01252 Orphenadrine
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01974 Centrally acting muscle relaxant
DG01252 Orphenadrine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 33
1 C1d C 30.7401 -20.6868
2 C1b C 29.5286 -21.3832
3 C1b C 31.9516 -21.3772
4 C6a C 31.4307 -19.4693
5 O1a O 30.0318 -19.4693
6 C6a C 28.3229 -20.6926
7 C6a C 31.9399 -22.7762
8 O6a O 30.7225 -18.2521
9 O6a O 32.8354 -19.4693
10 O6a O 27.1115 -21.3949
11 O6a O 28.3812 -19.2939
12 O6a O 33.1515 -23.4785
13 O6a O 30.7225 -23.4726
14 C1a C 15.8780 -22.1988
15 N1c N 17.0919 -21.4980
16 C1b C 18.3057 -22.1988
17 C1b C 19.5196 -21.4980
18 O2a O 20.7334 -22.1988
19 C1c C 21.9472 -21.4980
20 C8y C 23.1611 -22.1988
21 C8y C 21.9472 -20.0965
22 C8x C 23.1483 -19.4030
23 C8x C 23.1482 -18.0013
24 C8x C 21.9343 -17.3006
25 C8x C 20.7333 -17.9941
26 C8y C 20.7334 -19.3958
27 C8x C 23.1611 -23.6005
28 C8x C 24.3750 -24.3013
29 C8x C 25.5889 -23.6005
30 C8x C 25.5889 -22.1988
31 C8x C 24.3750 -21.4980
32 C1a C 19.5237 -20.0943
33 C1a C 17.0919 -20.0964
BOND 33
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 3 7 1
7 4 8 1
8 4 9 2
9 6 10 1
10 6 11 2
11 7 12 1
12 7 13 2
13 14 15 1
14 15 16 1
15 16 17 1
16 17 18 1
17 18 19 1
18 19 20 1
19 19 21 1
20 21 22 2
21 22 23 1
22 23 24 2
23 24 25 1
24 25 26 2
25 21 26 1
26 20 27 1
27 27 28 2
28 28 29 1
29 29 30 2
30 30 31 1
31 20 31 2
32 26 32 1
33 15 33 1
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