| Entry |
|
|---|
| Name |
Megestrol acetate (USP);
Megace (TN) |
|---|
| Product |
|
|---|
| Generic |
MEGESTROL ACETATE (Bryant Ranch Prepack), MEGESTROL ACETATE (Bryant Ranch Prepack), MEGESTROL ACETATE (Golden State Medical Supply), MEGESTROL ACETATE (Major Pharmaceuticals), MEGESTROL ACETATE (Major Pharmaceuticals), MEGESTROL ACETATE (McKesson Corporation dba SKY Packaging), MEGESTROL ACETATE (Natco Pharma USA LLC), MEGESTROL ACETATE (Par Pharmaceutical), MEGESTROL ACETATE (Par Pharmaceutical), MEGESTROL ACETATE (Pharmaceutical Associates), MEGESTROL ACETATE (Precision Dose), MEGESTROL ACETATE (Precision Dose), MEGESTROL ACETATE (Proficient Rx LP), MEGESTROL ACETATE (Strides Pharma Science Limited), MEGESTROL ACETATE (Strides Pharma Science Limited), MEGESTROL ACETATE (TWi Pharmaceuticals), MEGESTROL ACETATE (Teva Pharmaceuticals USA), MEGESTROL ACETATE (VistaPharm) |
|---|
| Formula |
C24H32O4
|
|---|
| Exact mass |
384.2301
|
|---|
| Mol weight |
384.5085
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00457): | D00952<US> |
|
|---|
| Efficacy |
Antineoplastic, Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC05 Megestrol
D00952 Megestrol acetate (USP) <US>
G03D PROGESTOGENS
G03DB Pregnadien derivatives
G03DB02 Megestrol
D00952 Megestrol acetate (USP) <US>
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02A HORMONES AND RELATED AGENTS
L02AB Progestogens
L02AB01 Megestrol
D00952 Megestrol acetate (USP) <US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Progestins
Megestrol
D00952 Megestrol acetate (USP)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00457 Megestrol
D00952 Megestrol acetate
DG01666 Progesterone receptor agonist
DG00457 Megestrol
D00952 Megestrol acetate
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG02004 Progesterone
D00952 Megestrol acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D00952 Megestrol acetate (USP) <US>
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00457 Megestrol
DG01666 Progesterone receptor agonist
DG00457 Megestrol
|
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| Other DBs |
|
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| LinkDB |
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| KCF data |
ATOM 28
1 C1z C 28.1137 -17.0472
2 C1z C 26.9253 -17.7170
3 C1x C 29.2906 -17.7287
4 O7a O 29.2906 -16.3538
5 C5a C 28.1722 -15.6723
6 C1y C 26.9837 -19.0862
7 C1x C 25.7544 -17.0296
8 C1a C 26.9079 -16.3481
9 C1x C 29.2789 -19.0978
10 C7a C 30.4789 -17.0355
11 C1a C 26.9020 -14.9789
12 O5a O 29.2848 -14.9732
13 C1y C 25.7311 -19.7677
14 C1x C 24.5601 -17.6996
15 C1a C 31.6616 -16.3481
16 O6a O 30.4732 -18.4104
17 C1y C 24.5484 -19.0686
18 C2x C 25.7311 -21.1368
19 C1z C 23.3599 -19.7503
20 C2y C 24.5368 -21.8184
21 C2y C 23.3542 -21.1252
22 C1x C 22.1774 -19.0629
23 C1a C 23.3484 -18.3812
24 C1a C 24.5951 -23.1875
25 C2x C 22.1774 -21.8184
26 C1x C 20.9832 -19.7503
27 C5x C 20.9832 -21.1252
28 O5x O 19.7946 -21.8067
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 4 10 1
10 5 11 1
11 5 12 2
12 6 13 1
13 7 14 1
14 10 15 1
15 10 16 2
16 13 17 1
17 13 18 1
18 17 19 1
19 18 20 2
20 19 21 1
21 19 22 1
22 19 23 1 #Up
23 20 24 1
24 21 25 2
25 22 26 1
26 25 27 1
27 27 28 2
28 6 9 1
29 14 17 1
30 20 21 1
31 26 27 1
|
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