KEGG   DRUG: Edrophonium chlorideHelp
Entry
D00994                      Drug                                   

Name
Edrophonium chloride (JP17/USP/INN);
Enlon (TN);
Tensilon (TN)
Formula
C10H16NO. Cl
Exact mass
201.092
Mol weight
201.6931
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01595  Cholinesterase inhibitor
  DG01593  Acetylcholinesterase inhibitor
Remark
Therapeutic category: 7229
Product: D00994<JP>
Efficacy
Antidote (to curare principles), Diagnostic aid (myasthenia gravis)
  Disease
Myasthenia gravis (emergency treatment) [DS:H01594]
Comment
Reversible cholinesterase inhibitor
Target
ACHE [HSA:43] [KO:K01049]
  Pathway
hsa04725  Cholinergic synapse
Interaction
Drug interaction
Structure map
map07220  Cholinergic and anticholinergic drugs
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 7  Agents not mainly for therapeutic purpose
  72  Intracorporeal diagnostic agents
   722  Various function testing reagents
    7229  Others
     D00994  Edrophonium chloride (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Carboxylic-ester hydrolases
    ACHE
     D00994  Edrophonium chloride (JP17/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00994  Edrophonium chloride
  D00994  Edrophonium chloride injection
BRITE hierarchy
Other DBs
CAS: 116-38-1
PubChem: 7848057
ChEBI: 4759
ChEMBL: CHEMBL1128
DrugBank: DB01010
LigandBox: D00994
NIKKAJI: J259.353J
LinkDB All DBs
KCF data Show

ATOM        13
            1   X   Cl   26.0173  -22.4203 #-
            2   C8y C    19.6834  -21.6392
            3   C8x C    19.6834  -23.0409
            4   C8x C    20.8974  -23.7418
            5   C8x C    22.1114  -23.0409
            6   C8y C    22.1114  -21.6392
            7   C8x C    20.8974  -20.9383
            8   O1a O    18.4695  -20.9383
            9   N1d N    23.3441  -20.9272 #+
            10  C1b C    24.5509  -21.6238
            11  C1a C    25.7348  -20.9402
            12  C1a C    23.3441  -19.5254
            13  C1a C    23.3441  -22.3290
BOND        12
            1     2   3 1
            2     3   4 2
            3     4   5 1
            4     5   6 2
            5     6   7 1
            6     2   7 2
            7     2   8 1
            8     6   9 1
            9     9  10 1
            10   10  11 1
            11    9  12 1
            12    9  13 1

» Japanese version   » Back

DBGET integrated database retrieval system