Homo sapiens (human): 43
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Entry
43 CDS
T01001
Symbol
ACHE, ACEE, ARACHE, N-ACHE, YT
Name
(RefSeq) acetylcholinesterase (Yt blood group)
KO
K01049
acetylcholinesterase [EC:
3.1.1.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00564
Glycerophospholipid metabolism
hsa04725
Cholinergic synapse
Drug target
Acotiamide:
D08838
<JP>
Ambenonium (
DG00990
):
D01001
<JP>
Benzgalantamine (
DG03314
):
D12930
D12931
<US>
Buntanetap (
DG03220
):
D12318
D12319
Demecarium:
D00667
Dimetacrine:
D02565
Distigmine (
DG00989
):
D01228
<JP>
Donepezil (
DG00983
):
D00670
<JP/US>
D07869
<JP>
Ecothiopate (
DG01131
):
D02193
<US>
Edrophonium:
D00994
<JP>
Fluostigmine:
D00043
Galantamine (
DG00985
):
D02173
<JP/US>
D04292
Gallamine:
D02292
Icopezil maleate:
D03751
Ipidacrine:
D09750
Itopride (
DG01395
):
D02729
<JP>
D08094
Ladostigil tartrate:
D03239
Latrepirdine (
DG01379
):
D09917
D09918
Neostigmine (
DG00987
):
D00995
<JP>
D00998
<JP/US>
D08261
Obidoxime:
D05215
Paraoxon:
D10529
Physostigmine (
DG01132
):
D00196
D02418
D03826
Pralidoxime (
DG01153
):
D00469
<US>
D01572
<JP>
D05590
Pyridostigmine (
DG00988
):
D00487
<JP/US>
Quilostigmine:
D03823
Rivastigmine (
DG00984
):
D02558
<US>
D03822
<JP/US>
Suronacrine maleate:
D05981
Tacrine (
DG00982
):
D02068
D08555
Velnacrine maleate:
D06288
Zanapezil fumarate:
D09835
Zifrosilone:
D06365
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
43 (ACHE)
09150 Organismal Systems
09156 Nervous system
04725 Cholinergic synapse
43 (ACHE)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
43 (ACHE)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.7 acetylcholinesterase
43 (ACHE)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:
hsa00537
]
Enzymes
43 (ACHE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
COesterase
AChE_tetra
BD-FAE
Abhydrolase_3
Motif
Other DBs
NCBI-GeneID:
43
NCBI-ProteinID:
NP_000656
OMIM:
100740
HGNC:
108
Ensembl:
ENSG00000087085
UniProt:
P22303
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:complement(100889994..100896994)
Genome browser
AA seq
614 aa
AA seq
DB search
MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPV
SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSM
NYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASV
GMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTEL
VACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVG
VVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPE
DPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGY
EIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQ
YVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQDRCSDL
NT seq
1845 nt
NT seq
+upstream
nt +downstream
nt
atgaggcccccgcagtgtctgctgcacacgccttccctggcttccccactccttctcctc
ctcctctggctcctgggtggaggagtgggggctgagggccgggaggatgcagagctgctg
gtgacggtgcgtgggggccggctgcggggcattcgcctgaagacccccgggggccctgtc
tctgctttcctgggcatcccctttgcggagccacccatgggaccccgtcgctttctgcca
ccggagcccaagcagccttggtcaggggtggtagacgctacaaccttccagagtgtctgc
taccaatatgtggacaccctatacccaggttttgagggcaccgagatgtggaaccccaac
cgtgagctgagcgaggactgcctgtacctcaacgtgtggacaccatacccccggcctaca
tcccccacccctgtcctcgtctggatctatgggggtggcttctacagtggggcctcctcc
ttggacgtgtacgatggccgcttcttggtacaggccgagaggactgtgctggtgtccatg
aactaccgggtgggagcctttggcttcctggccctgccggggagccgagaggccccgggc
aatgtgggtctcctggatcagaggctggccctgcagtgggtgcaggagaacgtggcagcc
ttcgggggtgacccgacatcagtgacgctgtttggggagagcgcgggagccgcctcggtg
ggcatgcacctgctgtccccgcccagccggggcctgttccacagggccgtgctgcagagc
ggtgcccccaatggaccctgggccacggtgggcatgggagaggcccgtcgcagggccacg
cagctggcccaccttgtgggctgtcctccaggcggcactggtgggaatgacacagagctg
gtagcctgccttcggacacgaccagcgcaggtcctggtgaaccacgaatggcacgtgctg
cctcaagaaagcgtcttccggttctccttcgtgcctgtggtagatggagacttcctcagt
gacaccccagaggccctcatcaacgcgggagacttccacggcctgcaggtgctggtgggt
gtggtgaaggatgagggctcgtattttctggtttacggggccccaggcttcagcaaagac
aacgagtctctcatcagccgggccgagttcctggccggggtgcgggtcggggttccccag
gtaagtgacctggcagccgaggctgtggtcctgcattacacagactggctgcatcccgag
gacccggcacgcctgagggaggccctgagcgatgtggtgggcgaccacaatgtcgtgtgc
cccgtggcccagctggctgggcgactggctgcccagggtgcccgggtctacgcctacgtc
tttgaacaccgtgcttccacgctctcctggcccctgtggatgggggtgccccacggctac
gagatcgagttcatctttgggatccccctggacccctctcgaaactacacggcagaggag
aaaatcttcgcccagcgactgatgcgatactgggccaactttgcccgcacaggggatccc
aatgagccccgagaccccaaggccccacaatggcccccgtacacggcgggggctcagcag
tacgttagtctggacctgcggccgctggaggtgcggcgggggctgcgcgcccaggcctgc
gccttctggaaccgcttcctccccaaattgctcagcgccaccgacacgctcgacgaggcg
gagcgccagtggaaggccgagttccaccgctggagctcctacatggtgcactggaagaac
cagttcgaccactacagcaagcaggatcgctgctcagacctgtga
DBGET
integrated database retrieval system
