KEGG   DRUG: Gestonorone caproateHelp
Entry
D01159                      Drug                                   

Name
Gestonorone caproate (JAN/USAN);
Depostat (TN)
Formula
C26H38O4
Exact mass
414.277
Mol weight
414.5775
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01666  Progesterone receptor agonist
 DG02004  Progesterone
Remark
Therapeutic category: 2479
ATC code: G03DA01 L02AB03
Product: D01159<JP>
Efficacy
Prostatic hyperplasia treatment, Progesterone receptor agonist
Comment
Progestin
Target
NR3C3 (PGR) [HSA:5241] [KO:K08556]
  Pathway
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
Interaction
Drug interaction
Structure map
map07226  Progesterone, androgen and estrogen receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03D PROGESTOGENS
    G03DA Pregnen (4) derivatives
     G03DA01 Gestonorone
      D01159  Gestonorone caproate (JAN/USAN) <JP>
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L02 ENDOCRINE THERAPY
   L02A HORMONES AND RELATED AGENTS
    L02AB Progestogens
     L02AB03 Gestonorone
      D01159  Gestonorone caproate (JAN/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   247  Estrogen and progesterone preparations
    2479  Others
     D01159  Gestonorone caproate (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C3 (PGR)
     D01159  Gestonorone caproate (JAN/USAN) <JP>
Drug classes of therapeutic agents [br08360.html]
 Endocrine and hormonal agents
  D01159
BRITE hierarchy
Other DBs
CAS: 1253-28-7
PubChem: 7848222
ChEBI: 31650
ChEMBL: CHEMBL2107389
LigandBox: D01159
NIKKAJI: J7.475F
LinkDB All DBs
KCF data Show

ATOM        30
            1   C1z C    31.6701  -16.0729
            2   C5a C    31.6615  -14.6986
            3   O5a O    32.8472  -14.0043
            4   C1a C    30.4673  -14.0190
            5   O7a O    32.8552  -15.3857
            6   C7a C    34.0419  -16.0727
            7   C1b C    35.2286  -15.3857
            8   C1b C    36.4153  -16.0727
            9   C1b C    37.6020  -15.3857
            10  C1b C    38.7886  -16.0727
            11  C1a C    39.9753  -15.3857
            12  O6a O    34.0419  -17.4467
            13  C1z C    30.4773  -16.7599
            14  C1y C    30.4773  -18.1339
            15  C1x C    32.8560  -18.1339
            16  C1x C    32.8560  -16.7599
            17  C1x C    24.5231  -18.7933
            18  C5x C    24.5231  -20.1674
            19  C2x C    25.7159  -20.8544
            20  C1x C    25.7159  -18.1063
            21  C1y C    26.9018  -18.7933
            22  C2y C    26.8958  -20.1674
            23  C1x C    28.0828  -20.8594
            24  C1x C    29.2758  -20.1775
            25  C1y C    28.0946  -18.1113
            26  C1y C    29.2758  -18.8063
            27  C1x C    29.2983  -16.0654
            28  C1x C    28.0358  -16.7409
            29  C1a C    30.4703  -15.3858
            30  O5x O    23.3334  -20.8549
BOND        33
            1     8   9 1
            2     1   5 1 #Down
            3     9  10 1
            4    17  18 1
            5    18  19 1
            6    19  22 2
            7    21  20 1
            8    20  17 1
            9     2   3 2
            10   10  11 1
            11    5   6 1
            12    6  12 2
            13   21  22 1
            14   22  23 1
            15   23  24 1
            16   24  26 1
            17   25  21 1
            18    1   2 1 #Up
            19    6   7 1
            20    2   4 1
            21    7   8 1
            22   25  26 1
            23   26  14 1
            24   13  27 1
            25   27  28 1
            26   28  25 1
            27   13  14 1
            28   13  29 1 #Up
            29   15  16 1
            30   16   1 1
            31    1  13 1
            32   14  15 1
            33   18  30 2

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