KEGG   DRUG: Remifentanil hydrochlorideHelp
Entry
D01177                      Drug                                   

Name
Remifentanil hydrochloride (JAN/USAN);
Ultiva (TN)
Product
  Generic
Formula
C20H28N2O5. HCl
Exact mass
412.1765
Mol weight
412.9077
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG02027  General anesthetics
  DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Remark
Therapeutic category: 8219
ATC code: N01AH06
Chemical structure group: DG00795
Product (DG00795): D01177<JP/US>
Efficacy
Analgesic, Opioid receptor agonist
Comment
opioid
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH06 Remifentanil
      D01177  Remifentanil hydrochloride (JAN/USAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 8  Narcotics
  82  Non-alkaloidal narcotics
   821  Synthetic narcotics
    8219  Others
     D01177  Remifentanil hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D01177  Remifentanil hydrochloride (JAN/USAN) <JP/US>
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D01177
BRITE hierarchy
Other DBs
CAS: 132539-07-2
PubChem: 7848240
ChEBI: 32091
ChEMBL: CHEMBL1201120
DrugBank: DB00899
LigandBox: D01177
LinkDB All DBs
KCF data Show

ATOM        28
            1   X   Cl   29.6535  -25.6624
            2   C8x C    16.9400  -27.3700
            3   C8x C    16.9400  -28.8400
            4   C8x C    18.1300  -29.5400
            5   C8x C    19.3900  -28.8400
            6   C8y C    19.3900  -27.3700
            7   C8x C    18.1300  -26.6000
            8   N1c N    20.6500  -26.6000
            9   C1z C    21.9100  -27.3700
            10  C1x C    21.9100  -28.8400
            11  C1x C    23.1000  -29.5400
            12  N1y N    24.3600  -28.8400
            13  C1x C    24.3600  -27.3700
            14  C1x C    23.1000  -26.6000
            15  C1b C    25.6200  -29.5400
            16  C1b C    26.8100  -28.8400
            17  C7a C    28.0700  -29.5400
            18  C5a C    20.6500  -25.2000
            19  O5a O    19.3900  -24.5000
            20  C1b C    21.9100  -24.5000
            21  C1a C    23.1000  -25.2000
            22  C7a C    21.1400  -28.5600
            23  O7a O    29.3300  -28.8400
            24  C1a C    30.5200  -29.5400
            25  O6a O    28.0000  -30.9400
            26  O7a O    21.1400  -29.9600
            27  C1a C    19.9276  -30.6600
            28  O6a O    19.9373  -28.1635
BOND        28
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     6   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 1
            12   12  13 1
            13   13  14 1
            14    9  14 1
            15   12  15 1
            16   15  16 1
            17   16  17 1
            18    8  18 1
            19   18  19 2
            20   18  20 1
            21   20  21 1
            22    9  22 1
            23   17  23 1
            24   23  24 1
            25   17  25 2
            26   22  26 1
            27   26  27 1
            28   22  28 2

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