| Entry |
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| Name |
Prednisolone sodium succinate (JP18/USP);
Kohakusanin (TN) |
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| Formula |
C25H31O8. Na
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| Exact mass |
482.1917
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| Mol weight |
482.50
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
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| Remark |
| Therapeutic category: | 2456 |
| Product (DG00093): | D00472<JP/US> D00980<JP/US> D00981<JP/US> D01239<JP> D03301<JP> |
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| Efficacy |
Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC04 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA01 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA04 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AA Corticosteroids, weak (group I)
D07AA03 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XA Corticosteroids, weak, other combinations
D07XA02 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB06 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD02 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA04 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB02 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA03 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA02 Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Glucocorticoids, Ophthalmic
Prednisolone
D01239 Prednisolone sodium succinate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2456 Prednisolones
D01239 Prednisolone sodium succinate (JP18/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
D01239 Prednisolone sodium succinate
Dermatological agent
DG03243 Atopic dermatitis agent
D01239 Prednisolone sodium succinate
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D01239 Prednisolone sodium succinate
Dermatological agent
DG03243 Atopic dermatitis agent
D01239 Prednisolone sodium succinate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D01239 Prednisolone sodium succinate (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01239 Prednisolone sodium succinate for injection
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00093 Prednisolone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 34
1 C1y C 21.9205 -19.8507
2 C1y C 20.7278 -20.4930
3 C1z C 21.9205 -18.4746
4 C1x C 24.3058 -19.8507
5 C1y C 19.5810 -19.8049
6 C1x C 20.7278 -21.8691
7 C1z C 23.1132 -17.8324
8 C1x C 20.7737 -17.7865
9 C1x C 24.3058 -18.5205
10 C1z C 18.3883 -20.4930
11 C1y C 19.5810 -18.4746
12 C1x C 19.5351 -22.5571
13 C5a C 23.1132 -16.1117
14 C2y C 18.3883 -21.8691
15 C2x C 17.1957 -19.8049
16 O1a O 18.3883 -17.7865
17 C1b C 24.2600 -15.4236
18 O5a O 21.9205 -15.4236
19 C2x C 17.1957 -22.5571
20 C2x C 16.0490 -20.4930
21 O7a O 25.4525 -16.1117
22 C5x C 16.0490 -21.8691
23 C7a C 26.5993 -15.4236
24 O5x O 14.8563 -22.5571
25 C1b C 27.7920 -16.1117
26 O6a O 26.5993 -14.0475
27 C1b C 28.9847 -15.4236
28 C6a C 30.1773 -16.1117
29 O6a O 31.3241 -15.4236 #-
30 O6a O 30.1773 -17.4878
31 C1a C 21.9205 -17.0965
32 C1a C 18.3883 -19.1148
33 O1a O 24.3066 -17.1433
34 Z Na 33.3900 -15.4700 #-
BOND 36
1 3 7 1
2 3 8 1
3 4 9 1
4 5 10 1
5 5 11 1
6 6 12 1
7 7 13 1 #Up
8 10 14 1
9 10 15 1
10 11 16 1 #Up
11 13 17 1
12 13 18 2
13 14 19 2
14 15 20 2
15 17 21 1
16 19 22 1
17 21 23 1
18 22 24 2
19 23 25 1
20 23 26 2
21 7 9 1
22 8 11 1
23 12 14 1
24 20 22 1
25 1 2 1
26 25 27 1
27 1 3 1
28 27 28 1
29 1 4 1
30 28 29 1
31 2 5 1
32 28 30 2
33 2 6 1
34 3 31 1 #Up
35 10 32 1 #Up
36 7 33 1 #Down
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