KEGG   DRUG: Oxazolam
Entry
D01278                      Drug                                   
Name
Oxazolam (JP18/INN);
Serenal (TN)
Formula
C18H17ClN2O2
Exact mass
328.0979
Mol weight
328.79
Structure
Simcomp
Class
Neuropsychiatric agent
 DG01567  GABA-A receptor agonist
 DG01914  Anxiolytics, benzodiazepine derivatives
Remark
Therapeutic category: 1124
Product: D01278<JP>
Efficacy
Antianxiety, Minor tranquilizer, Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
GABR [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Structure map
map07230  GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01278  Oxazolam (JP18/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG01567  GABA-A receptor agonist
   D01278  Oxazolam
  DG01914  Anxiolytics, benzodiazepine derivatives
   D01278  Oxazolam
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D01278  Oxazolam (JP18/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01278  Oxazolam
Narcotics and psychotropics in Japan [br08308.html]
 Psychotropics by Control Act Article 2 Table 31 (10 substances)
  D01278
Other DBs
CAS: 24143-17-7
PubChem: 7848341
ChEBI: 31944
LigandBox: D01278
NIKKAJI: J3.472J
LinkDB
KCF data

ATOM        23
            1   C1z C    20.9573  -14.7210
            2   C8y C    20.1233  -13.6220
            3   C8y C    20.4553  -12.2784
            4   N1x N    21.7041  -11.7057
            5   N1y N    22.3495  -14.6766
            6   C5x C    22.9456  -12.3221
            7   C1x C    23.2294  -13.6777
            8   C8x C    19.4578  -11.3193
            9   C8x C    18.1288  -11.7036
            10  C8y C    17.7968  -13.0473
            11  C8x C    18.7942  -14.0061
            12  O5x O    23.9797  -11.3967
            13  X   Cl   16.4452  -13.4380
            14  O2x O    20.5692  -16.0588
            15  C1y C    21.7216  -16.8413
            16  C1x C    22.8219  -15.9871
            17  C8y C    19.2724  -15.4137
            18  C8x C    18.0725  -14.7210
            19  C8x C    16.8726  -15.4137
            20  C8x C    16.8726  -16.7993
            21  C8x C    18.0725  -17.4921
            22  C8x C    19.2724  -16.7993
            23  C1a C    21.6975  -18.2684
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 1
            18    5  16 1
            19    1  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   20  21 1
            24   21  22 2
            25   17  22 1
            26   15  23 1

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