KEGG   DRUG: Methenolone acetate
Entry
D01375                      Drug                                   
Name
Methenolone acetate (USAN);
Metenolone acetate (JP18);
Primobolan (TN)
Formula
C22H32O3
Exact mass
344.2351
Mol weight
344.49
Structure
Simcomp
Class
Hormonal agent
 DG01590  Androgen receptor agonist
  DG01605  Anabolic steroid
Musculo-skeletal system agent
 DG03232  Osteoporosis agent
Remark
Therapeutic category: 2449
ATC code: A14AA04
Chemical structure group: DG00140
Product (DG00140): D01375<JP>
Efficacy
Anabolic, Androgen receptor agonist
Comment
Androstan derivative
Target
NR3C4 (AR) [HSA:367] [KO:K08557]
Interaction
Structure map
map07047  Osteoporosis drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A14 ANABOLIC AGENTS FOR SYSTEMIC USE
   A14A ANABOLIC STEROIDS
    A14AA Androstan derivatives
     A14AA04 Metenolone
      D01375  Methenolone acetate (USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   244  Anabolic steroid preparations
    2449  Others
     D01375  Methenolone acetate (USAN); Metenolone acetate (JP18)
Drug groups [BR:br08330]
 Hormonal agent
  DG01590  Androgen receptor agonist
   DG01605  Anabolic steroid
    DG00140  Metenolone
     D01375  Methenolone acetate
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   D01375  Methenolone acetate
Drug classes [BR:br08332]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   D01375  Methenolone acetate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C4 (AR)
     D01375  Methenolone acetate (USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01375  Metenolone acetate
Drug groups [BR:br08330]
 Hormonal agent
  DG01590  Androgen receptor agonist
   DG01605  Anabolic steroid
    DG00140  Metenolone
Other DBs
CAS: 434-05-9
PubChem: 7848438
ChEBI: 31828
LigandBox: D01375
NIKKAJI: J5.730D
LinkDB
KCF data

ATOM        25
            1   C2x C    21.5776  -20.7553
            2   C5x C    21.5776  -22.1266
            3   C1x C    22.7680  -22.8123
            4   C2y C    22.7680  -20.0697
            5   C1z C    23.9515  -20.7553
            6   C1y C    23.9457  -22.1266
            7   C1x C    25.1304  -22.8173
            8   C1x C    26.3208  -22.1368
            9   C1y C    25.1422  -20.0747
            10  C1y C    26.3210  -20.7683
            11  C1x C    26.3434  -18.0328
            12  C1x C    25.1533  -18.7070
            13  C1z C    27.5222  -18.7265
            14  C1y C    27.5058  -20.0900
            15  C1x C    29.8674  -20.1185
            16  C1x C    29.8841  -18.7551
            17  C1y C    28.7114  -18.0589
            18  O5x O    20.3904  -22.8128
            19  O7a O    28.7280  -16.6878
            20  C7a C    29.9238  -16.0166
            21  O6a O    29.8704  -14.6453
            22  C1a C    31.1029  -16.7165
            23  C1a C    27.5131  -17.3547
            24  C1a C    23.9394  -19.3840
            25  C1a C    22.7551  -18.6984
BOND        28
            1     3   6 1
            2     5   6 1
            3     6   7 1
            4     7   8 1
            5    13  14 1
            6    15  16 1
            7    16  17 1
            8    17  13 1
            9    14  15 1
            10    8  10 1
            11    2  18 2
            12    9   5 1
            13    5   4 1
            14    4   1 2
            15    1   2 1
            16   17  19 1 #Up
            17    9  10 1
            18   19  20 1
            19   10  14 1
            20   20  21 2
            21   13  11 1
            22   20  22 1
            23   11  12 1
            24   13  23 1 #Up
            25   12   9 1
            26    5  24 1 #Up
            27    2   3 1
            28    4  25 1

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