| Entry |
|
|---|
| Name |
Flurazepam hydrochloride (JP18);
Flurazepam monohydrochloride;
Dalmate (TN) |
|---|
| Formula |
C21H23ClFN3O. HCl
|
|---|
| Exact mass |
423.1280
|
|---|
| Mol weight |
424.34
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG03202 Hypnotic
DG01567 GABA-A receptor agonist
|
|---|
| Remark |
| Therapeutic category: | 1124 |
| Product (DG00919): | D00695<US> D01408<JP> |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CD Benzodiazepine derivatives
N05CD01 Flurazepam
D01408 Flurazepam hydrochloride (JP18) <JP>
USP drug classification [BR:br08302]
Sleep Disorder Agents
Sleep Promoting Agents
Flurazepam
D01408 Flurazepam hydrochloride (JP18)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D01408 Flurazepam hydrochloride (JP18)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG00919 Flurazepam
D01408 Flurazepam hydrochloride
DG03202 Hypnotic
DG00919 Flurazepam
D01408 Flurazepam hydrochloride
DG01567 GABA-A receptor agonist
DG00919 Flurazepam
D01408 Flurazepam hydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03202 Hypnotic
D01408 Flurazepam hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D01408 Flurazepam hydrochloride (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01408 Flurazepam hydrochloride
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D01408
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG00919 Flurazepam
DG03202 Hypnotic
DG00919 Flurazepam
DG01567 GABA-A receptor agonist
DG00919 Flurazepam
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 28
1 X Cl 36.6766 -12.5550
2 C2y C 31.7800 -13.0200
3 C8y C 30.9400 -11.9000
4 C8y C 31.2900 -10.5000
5 N1y N 32.5500 -9.9400
6 N2x N 33.2500 -13.0200
7 C5x C 33.8100 -10.5700
8 C1x C 34.0900 -11.9700
9 C8x C 30.3100 -9.5200
10 C8x C 28.9800 -9.9400
11 C8y C 28.6300 -11.2700
12 C8x C 29.6100 -12.2500
13 O5x O 34.8600 -9.6600
14 X Cl 27.2300 -11.6900
15 C8y C 31.1500 -14.2800
16 C8x C 29.7500 -14.2800
17 C8x C 29.0500 -15.4700
18 C8x C 29.7500 -16.6600
19 C8x C 31.1500 -16.6600
20 C8y C 31.8500 -15.4700
21 X F 33.3200 -15.4700
22 C1b C 32.5500 -8.5400
23 C1b C 33.7400 -7.9100
24 N1c N 33.7400 -6.4400
25 C1b C 35.0000 -5.7400
26 C1b C 32.5500 -5.7400
27 C1a C 31.3600 -6.4400
28 C1a C 36.1900 -6.4400
BOND 29
1 4 5 1
2 2 6 2
3 5 7 1
4 3 4 1
5 6 8 1
6 2 3 1
7 7 8 1
8 4 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 3 12 2
13 7 13 2
14 11 14 1
15 2 15 1
16 15 16 1
17 16 17 2
18 17 18 1
19 18 19 2
20 19 20 1
21 15 20 2
22 20 21 1
23 5 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 24 26 1
28 26 27 1
29 25 28 1
|
|---|
