| Entry |
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| Name |
Roxatidine acetate hydrochloride (JP18/USAN);
Altat (TN) |
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| Formula |
C19H28N2O4. HCl
|
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| Exact mass |
384.1816
|
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| Mol weight |
384.90
|
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| Structure |
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| Simcomp |
|
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| Class |
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
|
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| Remark |
| Therapeutic category: | 2325 |
| Product (DG00019): | D01467<JP> |
|
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| Efficacy |
Anti-ulcerative, H2 receptor antagonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07227 | Histamine H2/H3 receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BA H2-receptor antagonists
A02BA06 Roxatidine
D01467 Roxatidine acetate hydrochloride (JP18/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2325 H2 blockers
D01467 Roxatidine acetate hydrochloride (JP18/USAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
09 Histamine H2 receptor blocker containing drugs
D01467 Roxatidine acetate hydrochloride (JP18/USAN)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Roxatidine acetate hydrochloride
D01467 Roxatidine acetate hydrochloride (JP18/USAN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
DG00019 Roxatidine
D01467 Roxatidine acetate hydrochloride
Drug classes [BR:br08332]
Gastrointestinal agent
DG01481 Histamine receptor H2 antagonist
D01467 Roxatidine acetate hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH2
D01467 Roxatidine acetate hydrochloride (JP18/USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01467 Roxatidine acetate hydrochloride
D01467 Roxatidine acetate hydrochloride extended-release tablets
D01467 Roxatidine acetate hydrochloride extended-release capsules
D01467 Roxatidine acetate hydrochloride for injection
Rx-to-OTC switch list in Japan [br08314.html]
D01467
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
DG00019 Roxatidine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 N1b N 27.4400 -22.4000
2 C8x C 18.9700 -20.3000
3 C8y C 18.9700 -21.7000
4 C8x C 20.2300 -22.4000
5 C8y C 21.4200 -21.7000
6 C8x C 21.4200 -20.3000
7 C8x C 20.2300 -19.6000
8 O2a O 22.6800 -22.4000
9 C1b C 23.8700 -21.7000
10 C1b C 25.0600 -22.4000
11 C1b C 26.1800 -21.7000
12 C1b C 17.7800 -22.4000
13 N1y N 16.5900 -21.7000
14 C1x C 16.5900 -20.3000
15 C1x C 15.4000 -19.6000
16 C1x C 14.1400 -20.3000
17 C1x C 14.1400 -21.7000
18 C1x C 15.3300 -22.4000
19 C5a C 28.6300 -21.7000
20 C1b C 29.8200 -22.4000
21 O7a O 31.0100 -21.7000
22 C7a C 32.2000 -22.4000
23 C1a C 33.4600 -21.7000
24 O5a O 28.6300 -20.3000
25 O6a O 32.2000 -23.8000
26 X Cl 30.1700 -25.4800
BOND 26
1 6 7 2
2 7 2 1
3 13 18 1
4 14 15 1
5 15 16 1
6 16 17 1
7 17 18 1
8 8 9 1
9 9 10 1
10 2 3 2
11 10 11 1
12 11 1 1
13 8 5 1
14 1 19 1
15 19 20 1
16 3 4 1
17 20 21 1
18 3 12 1
19 21 22 1
20 4 5 2
21 22 23 1
22 12 13 1
23 19 24 2
24 13 14 1
25 22 25 2
26 5 6 1
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