| Entry |
|
|---|
| Name |
Meticrane (JP18/INN);
Arresten (TN) |
|---|
| Formula |
C10H13NO4S2
|
|---|
| Exact mass |
275.0286
|
|---|
| Mol weight |
275.35
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
|---|
| Comment |
Sulfonamide derivative
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
C03BA Sulfonamides, plain
C03BA09 Meticrane
D01605 Meticrane (JP18/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
D01605 Meticrane
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
D01605 Meticrane
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D01605 Meticrane (JP18/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01605 Meticrane
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 17
1 C1x C 11.4100 -18.1300
2 C1x C 11.4100 -19.5300
3 C1x C 12.6224 -20.2300
4 C8y C 13.8349 -19.5300
5 C8y C 13.8349 -18.1300
6 S2x S 12.6224 -17.4300
7 C8x C 15.0473 -20.2300
8 C8y C 16.2597 -19.5300
9 C8y C 16.2597 -18.1300
10 C8x C 15.0473 -17.4300
11 O3c O 13.6124 -16.4401
12 O3c O 11.6325 -16.4401
13 S4a S 17.4573 -17.4385
14 N1a N 18.6697 -16.7385
15 O3c O 16.7471 -16.2079
16 O3c O 18.1465 -18.6327
17 C1a C 17.4573 -20.2215
BOND 18
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 2
8 7 8 1
9 8 9 2
10 9 10 1
11 5 10 2
12 6 11 2
13 6 12 2
14 9 13 1
15 13 14 1
16 13 15 2
17 13 16 2
18 8 17 1
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