KEGG   DRUG: HaloxazolamHelp
Entry
D01758                      Drug                                   

Name
Haloxazolam (JP17/INN);
Somelin (TN)
Formula
C17H14BrFN2O2
Exact mass
376.0223
Mol weight
377.2077
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01835  Benzodiazepine sedative-hypnotics
 DG01567  GABA-A receptor agonist
Remark
Therapeutic category: 1124
Product: D01758<JP>
Efficacy
Sedative-hypnotic
Comment
Benzodiazepine derivative
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse
Interaction
Drug interaction
Structure map
map07032  Hypnotics
map07230  GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D01758  Haloxazolam (JP17/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABR
     D01758  Haloxazolam (JP17/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01758  Haloxazolam
Drug classes of therapeutic agents [br08360.html]
 Psychiatric agents
  D01758
BRITE hierarchy
Other DBs
CAS: 59128-97-1
PubChem: 7848821
ChEBI: 31666
ChEMBL: CHEMBL2104461
DrugBank: DB01476
LigandBox: D01758
NIKKAJI: J3.200J
LinkDB All DBs
KCF data Show

ATOM        23
            1   C1z C    16.5473  -15.5610
            2   C8y C    15.7133  -14.4620
            3   C8y C    16.0453  -13.1184
            4   N1x N    17.2941  -12.5457
            5   N1y N    17.9395  -15.5166
            6   C5x C    18.5356  -13.1621
            7   C1x C    18.8194  -14.5177
            8   C8x C    15.0478  -12.1593
            9   C8x C    13.7188  -12.5436
            10  C8y C    13.3868  -13.8873
            11  C8x C    14.3842  -14.8461
            12  O5x O    19.5697  -12.2367
            13  X   Br   12.0352  -14.2780
            14  O2x O    16.1592  -16.8988
            15  C1x C    17.3116  -17.6813
            16  C1x C    18.4119  -16.8271
            17  C8y C    14.8624  -16.2537
            18  C8x C    13.6625  -15.5610
            19  C8x C    12.4626  -16.2537
            20  C8x C    12.4626  -17.6393
            21  C8x C    13.6625  -18.3321
            22  C8y C    14.8624  -17.6393
            23  X   F    16.0688  -18.3359
BOND        26
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17   15  16 1
            18    5  16 1
            19    1  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   20  21 1
            24   21  22 2
            25   17  22 1
            26   22  23 1

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