KEGG   DRUG: Tripamide
Entry
D01895                      Drug                                   
Name
Tripamide (JAN/USAN/INN);
Normonal (TN)
Formula
C16H20ClN3O3S
Exact mass
369.0914
Mol weight
369.8663
Structure
Simcomp
Class
Cardiovascular agent
 DG03231  Antihypertensive
  DG02992  Thiazide related diuretic
 DG01690  Sulfonamide diuretic
  DG02992  Thiazide related diuretic
Remark
Therapeutic category: 2149
Efficacy
Antihypertensive, Na+Cl- symport inhibitor
Target
SLC12A3 (TSC) [HSA:6559] [KO:K14426]
Interaction
Structure map
map07017  Sulfonamide derivatives - diuretics
map07233  Ion transporter inhibitors
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D01895  Tripamide (JAN/USAN/INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG03231  Antihypertensive
   DG02992  Thiazide related diuretic
    D01895  Tripamide
  DG01690  Sulfonamide diuretic
   DG02992  Thiazide related diuretic
    D01895  Tripamide
Drug classes [BR:br08332]
 Cardiovascular agent
  DG02992  Thiazide related diuretic
   D01895  Tripamide
  DG03231  Antihypertensive
   D01895  Tripamide
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3 (TSC)
     D01895  Tripamide (JAN/USAN/INN)
Other DBs
CAS: 73803-48-2
PubChem: 7848957
ChEBI: 32264
LigandBox: D01895
NIKKAJI: J3.425H
LinkDB
KCF data

ATOM        24
            1   C1x C    15.6800  -16.9400
            2   N1y N    16.7300  -16.0300
            3   C1x C    16.1000  -14.7000
            4   N1b N    17.9200  -16.6600
            5   C5a C    19.1100  -15.9600
            6   C8y C    20.3700  -16.6600
            7   O5a O    19.1100  -14.6300
            8   C8x C    21.5600  -15.9600
            9   C8x C    20.3700  -18.0600
            10  C8y C    22.7500  -16.6600
            11  C8x C    21.4900  -18.7600
            12  C8y C    22.7500  -18.0600
            13  S4a S    23.9400  -16.0300
            14  X   Cl   23.8700  -18.7600
            15  O3c O    23.1000  -14.9100
            16  O3c O    24.8500  -17.2900
            17  N1a N    25.2000  -15.3300
            18  C1y C    14.7700  -14.9100
            19  C1y C    14.4900  -16.2400
            20  C1y C    13.1600  -16.7300
            21  C1x C    12.1100  -15.8200
            22  C1x C    12.3900  -14.4900
            23  C1y C    13.7200  -14.0000
            24  C1x C    12.8800  -15.2600
BOND        27
            1     6   9 2
            2     8  10 2
            3     9  11 1
            4    10  12 1
            5    10  13 1
            6    12  14 1
            7    13  15 2
            8    13  16 2
            9    13  17 1
            10    3  18 1
            11   11  12 2
            12    1   2 1
            13    1  19 1
            14    2   3 1
            15    2   4 1
            16    4   5 1
            17   18  19 1
            18   19  20 1
            19   20  21 1
            20   21  22 1
            21   22  23 1
            22   23  18 1
            23    5   6 1
            24   23  24 1 #Down
            25   20  24 1 #Down
            26    5   7 2
            27    6   8 1

» Japanese version   » Back

DBGET integrated database retrieval system