| Entry |
|
|---|
| Name |
Isoniazid sodium methanesulfonate hydrate (JAN);
Isoniazid sodium methanesulfonate monohydrate;
Isoniazid sodium methanesulfonate;
IHMS;
Neoiscotin (TN) |
|---|
| Formula |
C7H8N3O4S. Na. H2O
|
|---|
| Exact mass |
271.0239
|
|---|
| Mol weight |
271.23
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01966 Antitubercular
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
|
|---|
| Remark |
| Therapeutic category: | 6222 |
| Product (DG00642): | D00346<JP/US> D02002<JP> |
|
|---|
| Efficacy |
Antibacterial (tuberculostatic) |
|---|
| Comment |
Hydrazide
|
|---|
| Target |
enoyl-[acyl-carrier-protein] reductase (NADH) [KO: K11611] |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J04 ANTIMYCOBACTERIALS
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
J04AC Hydrazides
J04AC01 Isoniazid
D02002 Isoniazid sodium methanesulfonate hydrate (JAN) <JP>
USP drug classification [BR:br08302]
Antimycobacterials
Antituberculars
Isoniazid
D02002 Isoniazid sodium methanesulfonate hydrate (JAN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
622 Tuberculosis preparations
6222 Isoniazids
D02002 Isoniazid sodium methanesulfonate hydrate (JAN)
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG00642 Isoniazid
D02002 Isoniazid sodium methanesulfonate hydrate
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00642 Isoniazid
D02002 Isoniazid sodium methanesulfonate hydrate
Antimicrobials [BR:br08307]
Antibacterials
Other antibacterials
Mycolic acid biosynthesis inhibitor
D02002 Isoniazid sodium methanesulfonate hydrate (JAN) <JP>
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG00642 Isoniazid
Neuropsychiatric agent
DG01568 MAO inhibitor
DG01519 Non-selective monoamine oxidase inhibitor
DG00642 Isoniazid
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Other antibacterials
Mycolic acid biosynthesis inhibitor
DG00642 Isoniazid
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 17
1 N5x N 7.2800 -10.5700
2 C8x C 7.2800 -11.9700
3 C8x C 8.4924 -12.6700
4 C8y C 9.7049 -11.9700
5 C8x C 9.7049 -10.5700
6 C8x C 8.4924 -9.8700
7 C5a C 10.9424 -12.6700
8 N1b N 12.1549 -11.9700
9 N1b N 13.3673 -12.6700
10 C1b C 14.5797 -11.9700
11 S4a S 15.7922 -12.6700
12 O1d O 17.0046 -11.9700 #-
13 O5a O 10.9486 -14.0697
14 O1d O 14.8022 -13.6599
15 O1d O 16.7821 -13.6599
16 Z Na 18.8300 -11.9700 #+
17 O0 O 20.1600 -13.8600
BOND 15
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 7 13 2
14 11 14 2
15 11 15 2
|
|---|
