| Entry |
|
|---|
| Name |
Ketanserin (USAN/INN) |
|---|
| Formula |
C22H22FN3O3
|
|---|
| Exact mass |
395.1645
|
|---|
| Mol weight |
395.43
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Serotonin receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02K OTHER ANTIHYPERTENSIVES
C02KD Serotonin antagonists
C02KD01 Ketanserin
D02363 Ketanserin (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00265 Ketanserin
D02363 Ketanserin
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00265 Ketanserin
D02363 Ketanserin
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR2A
D02363 Ketanserin (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00265 Ketanserin
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00265 Ketanserin
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8y C 36.3464 -12.6205
2 C8y C 36.3464 -14.0201
3 N4x N 35.1335 -11.9208
4 C8x C 37.5594 -11.9208
5 C8y C 35.1335 -14.7198
6 C8x C 37.5594 -14.7198
7 C8y C 33.9206 -12.6205
8 C8x C 38.7723 -12.6205
9 N4y N 33.9206 -14.0201
10 O5x O 35.1335 -16.1194
11 C8x C 38.7723 -14.0201
12 O5x O 32.7076 -11.9208
13 C1b C 32.7076 -14.7198
14 C1b C 31.4947 -14.0201
15 N1y N 30.2818 -14.7198
16 C1x C 29.0688 -14.0201
17 C1x C 30.2818 -16.1194
18 C1x C 27.8559 -14.7198
19 C1x C 29.0688 -16.8191
20 C1y C 27.8559 -16.1194
21 C5a C 26.6440 -16.8193
22 O5a O 26.6442 -18.2187
23 C8y C 25.4430 -16.1258
24 C8x C 25.4437 -14.7004
25 C8x C 24.2316 -13.9998
26 C8y C 23.0189 -14.6992
27 C8x C 23.0181 -16.1246
28 C8x C 24.2302 -16.8252
29 X F 21.8155 -14.0036
BOND 32
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 2 6 2
6 3 7 1
7 4 8 1
8 5 9 1
9 5 10 2
10 6 11 1
11 7 12 2
12 9 13 1
13 13 14 1
14 14 15 1
15 15 16 1
16 15 17 1
17 16 18 1
18 17 19 1
19 18 20 1
20 7 9 1
21 8 11 2
22 19 20 1
23 20 21 1
24 21 22 2
25 21 23 1
26 23 24 2
27 24 25 1
28 25 26 2
29 26 27 1
30 27 28 2
31 23 28 1
32 26 29 1
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