KEGG   DRUG: ArtemetherHelp
Entry
D02483                      Drug                                   

Name
Artemether (JAN/USAN/INN)
Formula
C16H26O5
Exact mass
298.178
Mol weight
298.3746
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
ATC code: P01BE02
Product (mixture): D02484<JP/US>
Efficacy
Antimalarial
Comment
Artemisinin derivative
Target
Plasmodium falciparum sarcoplasmic/endoplasmic-reticulum Ca2+-ATPase (SERCA)
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
  P01 ANTIPROTOZOALS
   P01B ANTIMALARIALS
    P01BE Artemisinin and derivatives, plain
     P01BE02 Artemether
      D02483  Artemether (JAN/USAN/INN)
BRITE hierarchy
Other DBs
CAS: 71963-77-4
PubChem: 17396662
ChEBI: 195280
ChEMBL: CHEMBL2373867 CHEMBL411864 CHEMBL566534
LigandBox: D02483
NIKKAJI: J41.424G
LinkDB All DBs
KCF data Show

ATOM        21
            1   C1z C    19.5467  -15.4991
            2   C1y C    18.3421  -16.1916
            3   C1y C    20.7628  -16.2032
            4   C1y C    19.5526  -14.1142
            5   O2x O    17.9580  -15.3710
            6   O2x O    17.0386  -15.6795
            7   O2x O    18.3480  -17.5998
            8   C1y C    20.7628  -17.5998
            9   C1x C    21.9615  -15.5049
            10  C1y C    20.7628  -13.4158
            11  C1x C    18.8077  -13.0900
            12  O2x O    17.9639  -13.9803
            13  C1z C    16.6255  -14.3468
            14  C1y C    19.5526  -18.2980
            15  C1a C    21.9674  -18.2923
            16  C1x C    21.9615  -14.1142
            17  C1a C    20.7628  -12.0252
            18  C1x C    17.4111  -13.0609
            19  C1a C    15.2463  -14.3468
            20  O2a O    19.5583  -19.6887
            21  C1a C    18.3413  -20.3979
BOND        24
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Down
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 1
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14    8  15 1 #Up
            15    9  16 1
            16   10  17 1 #Down
            17   11  18 1
            18   13  19 1
            19   14  20 1 #Up
            20    8  14 1
            21   10  16 1
            22   13  12 1 #Down
            23   13  18 1
            24   20  21 1

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