KEGG   DRUG: ValganciclovirHelp
Entry
D02495                      Drug                                   

Name
Valganciclovir (INN)
Formula
C14H22N6O5
Exact mass
354.1652
Mol weight
354.3617
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Antiviral
 DG02840  Herpesvirus DNA polymerase inhibitor
 DG01937  Anti-cytomegalovirus agent
Remark
ATC code: J05AB14
Chemical structure group: DG00649
Product (DG00649): D03256<JP/US>
Efficacy
Antiviral, DNA polymerase ihibitor
Comment
Active form of prodrug: Ganciclovir [DR:D00333]
Acyclovir type
Target
Herpesvirus DNA polymerase [KO:K18964]
Interaction
Drug interaction
Structure map
map07044  Antiviral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB14 Valganciclovir
      D02495  Valganciclovir (INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-cytomegalovirus (CMV) Agents
   Valganciclovir
    D02495  Valganciclovir (INN)
Prodrugs [br08324.html]
 D02495
Prodrugs [br08324.html]
 DG00649
BRITE hierarchy
Other DBs
CAS: 175865-60-8
PubChem: 47205808
ChEBI: 63635
ChEMBL: CHEMBL1201314 CHEMBL400177
LigandBox: D02495
LinkDB All DBs
KCF data Show

ATOM        25
            1   C8y C    25.9159  -13.2779
            2   C8y C    25.9037  -11.8862
            3   N4y N    24.6925  -13.8432
            4   N4x N    27.2142  -13.9737
            5   N5x N    24.5569  -11.5468
            6   C8y C    27.0457  -11.1204
            7   C8x C    23.7876  -12.7095
            8   C8y C    28.3556  -13.2037
            9   N5x N    28.3394  -11.7424
            10  O5x O    27.0335   -9.7288
            11  N1a N    29.6498  -13.8297
            12  C1b C    24.6925  -15.2432
            13  O2a O    23.4862  -15.9399
            14  C1c C    22.3078  -15.2597
            15  C1b C    21.1120  -15.9503
            16  C1b C    22.3076  -13.8602
            17  O7a O    19.9247  -15.2650
            18  C7a C    18.7336  -15.9531
            19  C1c C    17.5439  -15.2664
            20  C1c C    16.3540  -15.9538
            21  O1a O    21.1119  -13.1699
            22  O6a O    18.7337  -17.3598
            23  C1a C    15.1637  -15.2667
            24  C1a C    16.3541  -17.3598
            25  N1a N    17.5435  -13.8603
BOND        26
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     6   9 1
            9     6  10 2
            10    8  11 1
            11    5   7 2
            12    8   9 2
            13    3  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   14  16 1
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   16  21 1
            23   18  22 2
            24   20  23 1
            25   20  24 1
            26   19  25 1 #Down

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