KEGG   DRUG: Balsalazide disodium
Entry
D02715                      Drug                                   
Name
Balsalazide disodium (USP);
Colazide (TN)
Product
COLAZAL (Salix Pharmaceuticals)
  Generic
BALSALAZIDE DISODIUM (Apotex Corp.), BALSALAZIDE DISODIUM (AvPAK), BALSALAZIDE DISODIUM (Bryant Ranch Prepack), BALSALAZIDE DISODIUM (Golden State Medical Supply), BALSALAZIDE DISODIUM (Hikma Pharmaceuticals USA), BALSALAZIDE DISODIUM (Oceanside Pharmaceuticals), BALSALAZIDE DISODIUM (PD-Rx Pharmaceuticals), BALSALAZIDE DISODIUM (Zydus Lifesciences Limited), BALSALAZIDE DISODIUM (Zydus Pharmaceuticals (USA))
Formula
C17H13N3O6. 2H2O. 2Na
Exact mass
437.0811
Mol weight
437.31
Structure
Simcomp
Class
Anti-inflammatory
 DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
  DG01909  Anti-inflammatory drug, salicylic acid derivatives
Remark
ATC code: A07EC04
Chemical structure group: DG00100
Product (DG00100): D02715<US>
Efficacy
Anti-inflammatory (gastrointestinal)
  Disease
Active ulcerative colitis [DS:H01466]
Comment
Salicylic acid derivative
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07E INTESTINAL ANTIINFLAMMATORY AGENTS
    A07EC Aminosalicylic acid and similar agents
     A07EC04 Balsalazide
      D02715  Balsalazide disodium (USP) <US>
USP drug classification [BR:br08302]
 Inflammatory Bowel Disease Agents
  Aminosalicylates and/or Prodrugs
   Balsalazide
    D02715  Balsalazide disodium (USP)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   DG01909  Anti-inflammatory drug, salicylic acid derivatives
    DG00100  Balsalazide
     D02715  Balsalazide disodium
Drug classes [BR:br08332]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   D02715  Balsalazide disodium
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D02715
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D02715
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
   DG01909  Anti-inflammatory drug, salicylic acid derivatives
    DG00100  Balsalazide
Other DBs
CAS: 150399-21-6
PubChem: 17396882
ChEBI: 59164
LigandBox: D02715
LinkDB
KCF data

ATOM        30
            1   C8y C    45.8756  -16.8673
            2   C8x C    45.8406  -18.2774
            3   N2b N    44.6584  -16.1651
            4   C8x C    47.1101  -16.2003
            5   C8y C    47.0458  -19.0091
            6   N2b N    43.4471  -16.8673
            7   C8x C    48.3157  -16.9259
            8   C8y C    48.2806  -18.3303
            9   C6a C    47.0108  -20.4193
            10  C8y C    42.2240  -16.1711
            11  O1a O    49.4860  -19.0677
            12  O6a O    45.7760  -21.0864
            13  O6a O    48.2163  -21.1449 #-
            14  C8x C    42.2240  -14.7607
            15  C8x C    41.0127  -16.8673
            16  C8x C    41.0127  -14.0527
            17  C8x C    39.7897  -16.1711
            18  C8y C    39.7897  -14.7607
            19  C5a C    38.5779  -14.0620
            20  N1b N    37.3736  -14.7585
            21  O5a O    38.5771  -12.6593
            22  C1b C    36.1812  -14.0709
            23  C1b C    34.9845  -14.7630
            24  C6a C    33.7881  -14.0732
            25  O6a O    32.5935  -14.7641 #-
            26  O6a O    33.7870  -12.6594
            27  Z   Na   30.2732  -14.7907 #+
            28  Z   Na   50.1654  -21.1101 #+
            29  O0  O    37.5897  -18.8552
            30  O0  O    37.5897  -18.8552
BOND        27
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 2
            5     3   6 2
            6     4   7 1
            7     5   8 1
            8     5   9 1
            9     6  10 1
            10    8  11 1
            11    9  12 2
            12    9  13 1
            13   10  14 1
            14   10  15 2
            15   14  16 2
            16   15  17 1
            17   16  18 1
            18    7   8 2
            19   17  18 2
            20   18  19 1
            21   19  20 1
            22   19  21 2
            23   20  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   24  26 2
BRACKET     1    35.0700  -19.8100   35.0700  -17.7100
            1    38.7800  -17.7100   38.7800  -19.8100
            1  2
 ORIGINAL  1   29
 REPEAT    1   30

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