| Entry |
|
|---|
| Name |
Alicaforsen sodium (USAN) |
|---|
| Formula |
C192H225N75O98P19S19. 19Na
|
|---|
| Exact mass |
6781.2693
|
|---|
| Mol weight |
6785.87
|
|---|
| Efficacy |
Anti-inflammatory, Translation inhibitor |
|---|
| Type |
Antisense oligonucleotide |
|---|
| Comment |
Treatment of steroid dependent Crohn's disease, ulcerative colitis, psoriasis, rheumatoid arthritis, and renal transplant (anti-ICAM-1 antisense)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04514 | Cell adhesion molecule (CAM) interaction |
| hsa04650 | Natural killer cell mediated cytotoxicity |
| hsa04670 | Leukocyte transendothelial migration |
|
|---|
| Brite |
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Cell adhesion molecules: Ig superfamiy
CAMs
ICAM1 (CD54)
D02811 Alicaforsen sodium (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
