KEGG   ORTHOLOGY: K06490
Entry
K06490                      KO                                     
Symbol
ICAM1, CD54
Name
intercellular adhesion molecule 1
Pathway
map04064  NF-kappa B signaling pathway
map04514  Cell adhesion molecules
map04650  Natural killer cell mediated cytotoxicity
map04668  TNF signaling pathway
map04670  Leukocyte transendothelial migration
map04933  AGE-RAGE signaling pathway in diabetic complications
map05143  African trypanosomiasis
map05144  Malaria
map05150  Staphylococcus aureus infection
map05164  Influenza A
map05166  Human T-cell leukemia virus 1 infection
map05167  Kaposi sarcoma-associated herpesvirus infection
map05169  Epstein-Barr virus infection
map05323  Rheumatoid arthritis
map05416  Viral myocarditis
map05417  Lipid and atherosclerosis
map05418  Fluid shear stress and atherosclerosis
Disease
H00083  Allograft rejection
H00361  Malaria
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04668 TNF signaling pathway
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04670 Leukocyte transendothelial migration
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05164 Influenza A
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05169 Epstein-Barr virus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09174 Infectious disease: parasitic
   05144 Malaria
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05143 African trypanosomiasis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09163 Immune disease
   05323 Rheumatoid arthritis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05418 Fluid shear stress and atherosclerosis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   05416 Viral myocarditis
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04090 CD molecules
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   00536 Glycosaminoglycan binding proteins
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
   04091 Lectins
    K06490  ICAM1, CD54; intercellular adhesion molecule 1
Exosome [BR:ko04147]
 Exosomal proteins
  Proteins found in most exosomes
   K06490  ICAM1, CD54; intercellular adhesion molecule 1
CD molecules [BR:ko04090]
 Proteins
  K06490  CD54, ICAM1; intercellular adhesion molecule 1
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K06490  ICAM1, CD54; intercellular adhesion molecule 1
Lectins [BR:ko04091]
 I-type lectins (Siglecs)
  K06490  ICAM1, CD54; intercellular adhesion molecule 1
Genes
HSA: 3383(ICAM1)
PTR: 450196(ICAM1)
PPS: 100980120(ICAM1)
GGO: 101127502(ICAM1)
PON: 100437727(ICAM1)
NLE: 100593834(ICAM1)
MCC: 712280(ICAM1)
MCF: 102138837(ICAM1)
CSAB: 103233893(ICAM1)
CATY: 105601438(ICAM1)
PANU: 101021731(ICAM1)
TGE: 112613138(ICAM1)
RRO: 104670485(ICAM1)
RBB: 108534474(ICAM1)
TFN: 117076602(ICAM1)
PTEH: 111527756(ICAM1)
CJC: 100393866(ICAM1)
SBQ: 101054438(ICAM1)
CSYR: 103262952(ICAM1)
MMUR: 105885597(ICAM1)
OGA: 100964084(ICAM1)
MMU: 15894(Icam1)
MCAL: 110301325(Icam1)
MPAH: 110327515(Icam1)
RNO: 25464(Icam1)
MCOC: 116073076(Icam1)
MUN: 110555772(Icam1)
CGE: 100689428(Icam1)
PLEU: 114695207(Icam1)
NGI: 103747569(Icam1)
HGL: 101713679(Icam1)
CPOC: 100717967(Icam1)
CCAN: 109693172(Icam1)
DORD: 105999070(Icam1)
DSP: 122119665(Icam1)
NCAR: 124968554
OCU: 100345640(ICAM1)
OPI: 101533287(ICAM1)
TUP: 102497624(ICAM1)
CFA: 403975(ICAM1)
VVP: 112909640(ICAM1)
VLG: 121495669(ICAM1)
AML: 100476475(ICAM1)
UMR: 103678731(ICAM1)
UAH: 113242979(ICAM1)
UAR: 123777616(ICAM1)
ELK: 111162530
LLV: 125084958
MPUF: 101683044(ICAM1)
ORO: 101375646(ICAM1)
EJU: 114197761(ICAM1)
ZCA: 113916701(ICAM1)
MLX: 118005126(ICAM1)
FCA: 101089421(ICAM1)
PYU: 121013964(ICAM1)
PBG: 122486853(ICAM1)
PTG: 102969345(ICAM1)
PPAD: 109254118(ICAM1)
AJU: 106980319(ICAM1)
HHV: 120244477(ICAM1)
BTA: 281839(ICAM1)
BIU: 109561581
BBUB: 102412194 102412516(ICAM1)
CHX: 102181113(ICAM1)
OAS: 443045(ICAM1)
ODA: 120863981(ICAM1)
CCAD: 122440432(ICAM1)
SSC: 396750(ICAM1)
CFR: 102509968(ICAM1)
CBAI: 105068375(ICAM1)
CDK: 105087642(ICAM1)
VPC: 102528180(ICAM1)
BACU: 103020269(ICAM1)
LVE: 103079699(ICAM1)
OOR: 101276958(ICAM1)
DLE: 111166053(ICAM1)
PCAD: 102988478(ICAM1)
PSIU: 116751656(ICAM1)
ECB: 100058207(ICAM1)
EPZ: 103558066(ICAM1)
EAI: 106841519(ICAM1)
MYB: 102255343(ICAM1)
MYD: 102767600(ICAM1)
MMYO: 118658133(ICAM1)
MLF: 102436833(ICAM1)
MNA: 107533247(ICAM1)
PKL: 118731218(ICAM1)
HAI: 109391654(ICAM1)
DRO: 112301541(ICAM1)
AJM: 119037076(ICAM1)
PDIC: 114503655(ICAM1)
PHAS: 123828517(ICAM1)
MMF: 118615517(ICAM1)
RFQ: 117038369(ICAM1)
PALE: 102897326(ICAM1)
PGIG: 120610878(ICAM1)
PVP: 105305590(ICAM1)
RAY: 107515099(ICAM1)
MJV: 108397119
TOD: 119240938(ICAM1)
SARA: 101549044(ICAM1)
LAV: 100673685(ICAM1)
TMU: 101343257
DNM: 101427372(ICAM1)
SHR: 100933797(ICAM1)
PCW: 110214227
PRUF: 121364119
DNE: 112983429
ASN: 102381642
PSS: 102449607
CABI: 116832449
SUND: 121922825
SANH: 107670523
SLAL: 111651278
OGO: 123998937
PKI: 111849269
 » show all
Reference
PMID:3340213
  Authors
Simmons D, Makgoba MW, Seed B
  Title
ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM.
  Journal
Nature 331:624-7 (1988)
DOI:10.1038/331624a0
  Sequence
[hsa:3383]
Reference
  Authors
Braun M, Pietsch P, Schror K, Baumann G, Felix SB
  Title
Cellular adhesion molecules on vascular smooth muscle cells.
  Journal
Cardiovasc Res 41:395-401 (1999)
DOI:10.1016/S0008-6363(98)00302-2
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