KEGG   DRUG: Aptiganel hydrochloride
Entry
D02973                      Drug                                   

Name
Aptiganel hydrochloride (USAN)
Formula
C20H21N3. HCl
Exact mass
339.1502
Mol weight
339.8618
Structure
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Efficacy
Stroke treatment, NMDA receptor antagonist
Comment
Stroke and traumatic brain injury treatment
Target
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D02973  Aptiganel hydrochloride (USAN)
Other DBs
CAS: 137160-11-3
PubChem: 17397130
LigandBox: D02973
LinkDB
KCF data

ATOM        24
            1   C8y C    12.2500  -18.2700
            2   C8y C    12.2500  -19.6700
            3   C8x C    13.4624  -20.3700
            4   C8x C    14.6749  -19.6700
            5   C8y C    14.6749  -18.2700
            6   C8x C    13.4624  -17.5700
            7   C8x C    11.0376  -17.5700
            8   C8x C     9.8251  -18.2700
            9   C8x C     9.8251  -19.6700
            10  C8x C    11.0376  -20.3700
            11  N2a N    17.0997  -19.6700
            12  C2c C    17.0997  -18.2700
            13  N1b N    15.8873  -17.5700
            14  C8x C    19.5246  -19.6700
            15  C8y C    19.5246  -18.2700
            16  N1c N    18.3122  -17.5700
            17  C8x C    20.7370  -20.3700
            18  C8x C    21.9495  -19.6700
            19  C8y C    21.9495  -18.2700
            20  C8x C    20.7370  -17.5700
            21  C1a C    24.3744  -18.2700
            22  C1b C    23.1619  -17.5700
            23  C1a C    18.3122  -16.1703
            24  X   Cl   28.9800  -19.7400
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11   10   2 1
            12   11  12 2
            13   12  13 1
            14    5  13 1
            15   14  15 1
            16   15  16 1
            17   12  16 1
            18   14  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   15  20 2
            23   21  22 1
            24   19  22 1
            25   16  23 1

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