| Entry |
|
|---|
| Name |
Arformoterol tartrate (USAN);
Brovana (TN) |
|---|
| Product |
|
|---|
| Generic |
ARFORMOTEROL TARTRATE (Alembic Pharmaceuticals), ARFORMOTEROL TARTRATE (American Health Packaging), ARFORMOTEROL TARTRATE (Cipla USA), ARFORMOTEROL TARTRATE (Dr. Reddy's Laboratories), ARFORMOTEROL TARTRATE (Fosun Pharma USA), ARFORMOTEROL TARTRATE (Ingenus Pharmaceuticals), ARFORMOTEROL TARTRATE (Lifestar Pharma LLC), ARFORMOTEROL TARTRATE (Lupin Pharmaceuticals), ARFORMOTEROL TARTRATE (Micro Labs Limited), ARFORMOTEROL TARTRATE (NorthStar RxLLC), ARFORMOTEROL TARTRATE (Sun Pharmaceutical Industries), ARFORMOTEROL TARTRATE (Teva Pharmaceuticals USA), ARFORMOTEROL TARTRATE INHALATION (Slate Run Pharmaceuticals), ARFORMOTEROL TARTRATE INHALATION SOLUTION (Aucta Pharmaceuticals), ARFORMOTEROL TARTRATE INHALATION SOLUTION (Ritedose Pharmaceuticals) |
|---|
| Formula |
C19H24N2O4. C4H6O6
|
|---|
| Exact mass |
494.1900
|
|---|
| Mol weight |
494.49
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
|
|---|
| Remark |
| Product (DG01233): | D02981<US> |
|
|---|
| Efficacy |
Antiasthmatic, Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Disease |
Chronic obstructive pulmonary disease [DS: H01714] |
|---|
| Comment |
Phenethylamine derivative
Long-acting beta-adrenoceptor agonist (LABA)
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
Bronchodilators, Sympathomimetic
Arformoterol
D02981 Arformoterol tartrate (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01233 Arformoterol
D02981 Arformoterol tartrate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D02981 Arformoterol tartrate (USAN) <US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D02981
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01233 Arformoterol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 35
1 C8y C 17.4888 -18.1875
2 C8x C 16.2298 -18.8869
3 C8x C 17.4888 -16.7886
4 C1c C 18.6779 -18.8869
5 C8y C 15.0407 -18.1875
6 C8x C 16.2298 -16.0891
7 C1b C 19.8670 -18.1875
8 C8y C 15.0407 -16.7886
9 N1b N 13.8517 -18.8869
10 N1b N 21.0560 -18.8869
11 O1a O 13.8517 -16.0891
12 C4a C 12.5927 -18.1875
13 C1c C 22.3151 -18.1875
14 O4a O 11.4036 -18.8869
15 C1b C 23.5041 -18.8869
16 C8y C 24.6932 -18.1875
17 C8x C 24.6932 -16.7886
18 C8x C 25.8823 -18.8869
19 C8x C 25.8823 -16.0891
20 C8x C 27.1413 -18.1875
21 C8y C 27.1413 -16.7886
22 O2a O 28.3303 -16.0192
23 C1a C 29.5194 -16.7186
24 C1a C 22.3151 -16.7886
25 O1a O 18.6779 -20.2858
26 O6a O 22.8666 -22.8766
27 C6a C 24.0556 -22.1771
28 C1c C 25.3147 -22.8766
29 C1c C 26.5037 -22.1771
30 C6a C 27.6928 -22.8766
31 O6a O 24.0556 -20.7782
32 O6a O 28.9518 -22.1771
33 O6a O 27.6928 -24.2755
34 O1a O 25.3147 -24.2755
35 O1a O 26.5037 -20.7782
BOND 35
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 5 8 2
8 5 9 1
9 7 10 1
10 8 11 1
11 9 12 1
12 10 13 1
13 12 14 2
14 13 15 1
15 15 16 1
16 16 17 2
17 16 18 1
18 17 19 1
19 18 20 2
20 19 21 2
21 21 22 1
22 22 23 1
23 6 8 1
24 20 21 1
25 13 24 1 #Down
26 4 25 1 #Down
27 26 27 1
28 27 28 1
29 28 29 1
30 29 30 1
31 27 31 2
32 30 32 1
33 30 33 2
34 28 34 1 #Up
35 29 35 1 #Up
|
|---|
