DRUG: Binetrakin
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Entry
D03117 Drug
Name
Binetrakin (USAN/INN)
Sequence
HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE
KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM
REKYSKCSS
(Disulfide bridge: 3-127, 24-65, 46-99)
Type
Peptide
Efficacy
Antineoplastic, Antirheumatic, Immunomodulator
Comment
interleukin 4 (IL4) analog [HSA:
3565
] [KO:
K05430
]
Treatment of gastrointestinal carcinoma, rheumatoid arthritis and dendritic cell activation (immunomodulatory activities on B cells, macrophages, eosinophils and other hematopoietic cells)
Target
IL4 [HSA:
3565
] [KO:
K05430
]
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04151
PI3K-Akt signaling pathway
hsa04630
JAK-STAT signaling pathway
hsa04664
Fc epsilon RI signaling pathway
Brite
Target-based classification of drugs [BR:
br08310
]
Cytokines and receptors
Cytokines
Interleukins
IL4
D03117 Binetrakin (USAN/INN)
BRITE hierarchy
Other DBs
CAS:
207137-56-2
PubChem:
17397272
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