KEGG ORTHOLOGY: K05430

ORTHOLOGY: K05430

Entry

K05430                      KO

Symbol

IL4

Name

interleukin 4

Pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04630

JAK-STAT signaling pathway

map04640

Hematopoietic cell lineage

map04657

IL-17 signaling pathway

map04658

Th1 and Th2 cell differentiation

map04659

Th17 cell differentiation

map04660

T cell receptor signaling pathway

map04664

Fc epsilon RI signaling pathway

map04672

Intestinal immune network for IgA production

map05140

Leishmaniasis

map05200

Pathways in cancer

map05310

Asthma

map05320

Autoimmune thyroid disease

map05321

Inflammatory bowel disease

map05330

Allograft rejection

Disease

H00079

Asthma

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05430  IL4; interleukin 4
   04151 PI3K-Akt signaling pathway
    K05430  IL4; interleukin 4
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05430  IL4; interleukin 4
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05430  IL4; interleukin 4
   04660 T cell receptor signaling pathway
    K05430  IL4; interleukin 4
   04658 Th1 and Th2 cell differentiation
    K05430  IL4; interleukin 4
   04659 Th17 cell differentiation
    K05430  IL4; interleukin 4
   04657 IL-17 signaling pathway
    K05430  IL4; interleukin 4
   04664 Fc epsilon RI signaling pathway
    K05430  IL4; interleukin 4
   04672 Intestinal immune network for IgA production
    K05430  IL4; interleukin 4
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05430  IL4; interleukin 4
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    K05430  IL4; interleukin 4
  09163 Immune disease
   05310 Asthma
    K05430  IL4; interleukin 4
   05320 Autoimmune thyroid disease
    K05430  IL4; interleukin 4
   05321 Inflammatory bowel disease
    K05430  IL4; interleukin 4
   05330 Allograft rejection
    K05430  IL4; interleukin 4
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides
    K05430  IL4; interleukin 4
   00536 Glycosaminoglycan binding proteins
    K05430  IL4; interleukin 4
Cytokines and neuropeptides [BR:ko04052]
Cytokines
  Interleukins
   K05430  IL4; interleukin 4
Glycosaminoglycan binding proteins [BR:ko00536]
Heparan sulfate / Heparin
  Cytokines
   K05430  IL4; interleukin 4

Other DBs

GO:

0005136

Genes

HSA:

3565(IL4)

PTR:	449565(IL4)

PPS:	100988878(IL4)

GGO:	101140015(IL4)

PON:	100451705(IL4)

PPYG:

129036373(IL4)

NLE:	100597165(IL4)

HMH:	116470836(IL4)

SSYN:

129493362(IL4)

MCC:	574281(IL4)

MCF:	107130068(IL4)

MTHB:

126956021

MNI:	105467168(IL4)

CSAB:

103244520(IL4)

CATY:

105599747(IL4)

PANU:

100126747(IL4)

TGE:	112626412(IL4)

MLEU:

105531344(IL4)

RRO:	104659834(IL4)

RBB:	108529583(IL4)

TFN:	117065885(IL4)

PTEH:

111529515(IL4)

CANG:

105518194(IL4)

CJC:	100406536(IL4)

SBQ:	101038267(IL4)

CIMI:

108307166(IL4)

ANAN:

105711654(IL4)

CSYR:

103259257(IL4)

MMUR:

105869954(IL4)

LCAT:

123637755(IL4)

PCOQ:

105816021(IL4)

OGA:	100946038(IL4)

MMU:	16189(Il4)

MCAL:

110306003(Il4)

MPAH:

110332760(Il4)

RNO:	287287(Il4)

MCOC:

116078788(Il4)

ANU:	117710319(Il4)

ASYL:

127695269(Il4)

MUN:	110548759(Il4)

CGE:	100755642(Il4)

MAUA:

101843742(Il4)

PROB:

127219302(Il4)

PLEU:

114681924(Il4)

MORG:

121445651(Il4)

MFOT:

126510971

AAMP:

119811116(Il4)

NGI:	103747047(Il4)

HGL:	101706414(Il4)

CPOC:

100720403(Il4)

CCAN:

109694185(Il4)

DORD:

105996721(Il4)

DSP:	122115397(Il4)

NCAR:

124986432

MMMA:

107148001(Il4)

OCU:	100302454(IL4)

OPI:	101524093(IL4)

TUP:	102483778(IL4)

GVR:	103589624(IL4)

CFA:	403785(IL4)

VVP:	112917033(IL4)

VLG:	121496081(IL4)

NPO:	129494903(IL4)

AML:	100482473(IL4)

UMR:	103663832(IL4)

UAH:	113261716(IL4)

UAR:	123790366(IL4)

ELK:

111141099

LLV:

125100382

MPUF:

101686417(IL4)

MNP:	132027869(IL4)

MLK:	131831369(IL4)

NVS:	122901601(IL4)

ORO:	101384443(IL4)

EJU:	114209547(IL4)

ZCA:	113929402(IL4)

MLX:	118017175(IL4)

NSU:	110590985(IL4)

LWW:	102750729(IL4)

FCA:	751514(IL4)

PYU:	121010879(IL4)

PCOO:

112861021(IL4)

PBG:	122472844(IL4)

PVIV:

125171069(IL4)

LRUF:

124523858

PTG:	102963113(IL4)

PPAD:

109250887(IL4)

PUC:

125935484

AJU:

106970698

HHV:	120223325(IL4)

BTA:	280824(IL4)

BOM:	102272045(IL4)

BIU:	109561213(IL4)

BBUB:

102397131(IL4)

BBIS:

105005564(IL4)

CHX:	100860814(IL4)

OAS:	101122781(IL4)

BTAX:

128051558(IL4)

CSUM:

138086101(IL4)

ODA:	120864752(IL4)

CCAD:

122439281(IL4)

MREE:

136167044(IL4)

MBEZ:

129558702(IL4)

SSC:	397225(IL4)

CFR:	102515500(IL4)

CBAI:

105082107(IL4)

CDK:	105090136(IL4)

VPC:	102541329(IL4)

BACU:

103010027(IL4)

BMUS:

118892463(IL4)

LVE:	103069012(IL4)

OOR:	101290331(IL4)

DLE:	111182418(IL4)

PCAD:

102983897(IL4)

PSIU:

116751393(IL4)

NASI:

112401382(IL4)

ECB:	100034225(IL4)

EPZ:	103563367(IL4)

EAI:	106841015(IL4)

MYB:	102243627(IL4)

MYD:	102773980(IL4)

MMYO:

118657905(IL4)

MLF:	102437928(IL4)

MDT:	132236148(IL4)

PKL:	118711589(IL4)

EFUS:

103290101(IL4)

MNA:	107525027(IL4)

DRO:	112318159(IL4)

SHON:

118990129(IL4)

AJM:	119037707(IL4)

PDIC:

114510341(IL4)

PHAS:

123812938(IL4)

MMF:	118616277(IL4)

PPAM:

129066327(IL4)

HAI:	109382592(IL4)

RFQ:	117017057(IL4)

PALE:

102890025(IL4)

PGIG:

120616686(IL4)

PVP:	105293550(IL4)

RAY:	107497063(IL4)

MJV:	108390065(IL4)

TOD:	119243728(IL4)

SARA:

101539338(IL4)

SFUM:

130033065(IL4)

SETR:

126028368(IL4)

LAV:	100674484(IL4)

TMU:

101341010

ETF:	101653709(IL4)

DNM:	101420628(IL4)

GAS:	123233889(IL4)

SHR:	100914681(IL4)

PCW:	110211817(IL4)

TVP:	118841351(IL4)

PBRV:

138173679(IL4)

GGA:	416330(IL4)

NMEL:

110405326(IL4)

ACYG:

106032665

CATA:

118254981(IL4)

AFUL:

116494649(IL4)

TGU:

100231557

OTC:

121332428

PRUF:

121361464

FAB:	101822266(IL4)

ACOE:

138118353(IL4)

ETL:	114070738(IL4)

MMEA:

130583993(IL4)

HRT:	120759362(IL4)

SATI:

136367760(IL4)

FPG:	101920907(IL4)

FCH:

102059582

NNT:	104407025(IL4)

SHAB:

115616044(IL4)

ACUN:

113485357(IL4)

ACHC:

115334326(IL4)

AGEN:

126050785

HHAR:

128134464(IL4)

GCL:

127022176

LDI:	104352758(IL4)

PPUS:

135185476(IL4)

EGZ:	104133729(IL4)

NNI:

104012053

PADL:

103915856(IL4)

AFOR:

103904589(IL4)

FGA:	104079596(IL4)

PGUU:

104468070(IL4)

CPEA:

104391890(IL4)

CVF:	104291981(IL4)

NPD:	112952713(IL4)

DNE:

112994150

SCAM:

104147025

ASN:	102374890(IL4)

TST:

117881532

DRE:	100188894(il4)

CCAR:

109064937

CAUA:

113078138

CGIB:

128027363

PTET:

122357735(il4)

LROH:

127176371(il4)

OMC:	131553278(il4)

PPRM:

120461073(il4)

RKG:	130084822(il4)

CERY:

137005067(il4)

TROS:

130563397(il4)

TDW:	130438518(il4)

MANU:

129422938(il4)

CMK:

RTP:

CPLA:

Reference

PMID:2535858

Authors

Arai N, Nomura D, Villaret D, DeWaal Malefijt R, Seiki M, Yoshida M, Minoshima S, Fukuyama R, Maekawa M, Kudoh J, et al.

Title

Complete nucleotide sequence of the chromosomal gene for human IL-4 and its expression.

Journal

J Immunol 142:274-82 (1989)

Sequence

[hsa:3565]

LinkDB

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