| Entry |
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| Name |
Diphenhydramine laurylsulfate (JAN);
Vena (TN) |
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| Formula |
C12H26O4S. C17H21NO
|
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| Exact mass |
521.3175
|
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| Mol weight |
521.75
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| Structure |
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
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| Remark |
| Product (DG00390): | D00300<JP> D00669<JP/US> D00520<JP/US> |
|
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| Efficacy |
Antiallergic, H1 receptor antagonist |
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| Comment |
Diphenhydramine derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA32 Diphenhydramine
D03360 Diphenhydramine laurylsulfate (JAN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA02 Diphenhydramine
D03360 Diphenhydramine laurylsulfate (JAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D03360 Diphenhydramine laurylsulfate (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
Third-class OTC drugs
Inorganic and organic chemicals
Diphenhydramine
D03360 Diphenhydramine laurylsulfate (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00390 Diphenhydramine
D03360 Diphenhydramine laurylsulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D03360 Diphenhydramine laurylsulfate (JAN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00390 Diphenhydramine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 36
1 C1c C 20.7534 -18.7629
2 C8y C 19.5421 -19.4675
3 C8y C 21.9707 -19.4675
4 O2a O 20.7593 -17.3651
5 C8x C 19.5421 -20.8712
6 C8x C 18.3306 -18.7629
7 C8x C 21.9650 -20.8712
8 C8x C 23.1762 -18.7629
9 C1b C 21.9707 -16.6604
10 C8x C 18.3306 -21.5641
11 C8x C 17.1133 -19.4675
12 C8x C 23.1762 -21.5641
13 C8x C 24.3935 -19.4675
14 C8x C 17.1133 -20.8712
15 C8x C 24.3876 -20.8712
16 C1b C 23.2072 -17.3717
17 N1c N 24.4042 -16.6780
18 C1a C 25.5940 -17.3624
19 C1a C 24.4020 -15.2685
20 C1b C 43.4700 -19.3900
21 C1b C 42.2800 -20.0900
22 C1b C 41.0900 -19.3900
23 C1b C 39.8300 -20.0900
24 C1b C 38.6400 -19.3900
25 C1b C 37.4500 -20.0900
26 C1b C 36.2600 -19.3900
27 C1b C 35.0700 -20.0900
28 C1b C 33.8100 -19.3900
29 C1b C 32.6200 -20.0900
30 C1b C 31.4300 -19.3900
31 O2a O 30.2400 -20.0900
32 C1a C 44.7300 -20.0900
33 S4a S 28.8400 -20.0900
34 O1d O 27.4400 -20.0900
35 O1d O 28.8400 -18.6900
36 O1d O 28.8400 -21.4900
BOND 36
1 5 10 2
2 6 11 1
3 7 12 1
4 8 13 2
5 10 14 1
6 12 15 2
7 11 14 2
8 13 15 1
9 1 2 1
10 1 3 1
11 1 4 1
12 2 5 1
13 2 6 2
14 3 7 2
15 3 8 1
16 4 9 1
17 9 16 1
18 16 17 1
19 17 18 1
20 17 19 1
21 20 21 1
22 21 22 1
23 22 23 1
24 23 24 1
25 24 25 1
26 25 26 1
27 26 27 1
28 27 28 1
29 28 29 1
30 29 30 1
31 30 31 1
32 20 32 1
33 31 33 1
34 33 34 1
35 33 35 2
36 33 36 2
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