| Entry |
|
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| Name |
Estradiol acetate (USAN);
Femring (TN) |
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| Product |
|
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| Formula |
C20H26O3
|
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| Exact mass |
314.1882
|
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| Mol weight |
314.42
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Hormonal agent
DG01986 Estrogen
DG01584 Estrogen receptor agonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Product (DG00462): | D00105<JP/US> D01413<JP/US> D04061<US> D04063<US> D07918<US> |
|
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| Efficacy |
Menstruation disorder agent, Estrogen receptor agonist |
|---|
| Comment |
Estrogen
Estrogen replacement therapy
|
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| Target |
|
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| Pathway |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
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| Interaction |
|
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| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03C ESTROGENS
G03CA Natural and semisynthetic estrogens, plain
G03CA03 Estradiol
D04061 Estradiol acetate (USAN) <US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Estrogens
Estradiol
D04061 Estradiol acetate (USAN)
Drug groups [BR:br08330]
Hormonal agent
DG01986 Estrogen
DG00462 Estradiol
D04061 Estradiol acetate
DG01584 Estrogen receptor agonist
DG00462 Estradiol
D04061 Estradiol acetate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00462 Estradiol
D04061 Estradiol acetate
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG01986 Estrogen
D04061 Estradiol acetate
DG01584 Estrogen receptor agonist
D04061 Estradiol acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
Estrogen receptor
NR3A (ESR)
D04061 Estradiol acetate (USAN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D04061
Drug groups [BR:br08330]
Hormonal agent
DG01986 Estrogen
DG00462 Estradiol
DG01584 Estrogen receptor agonist
DG00462 Estradiol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00462 Estradiol
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 C1y C 24.1371 -17.4005
2 C1y C 22.9558 -18.0789
3 C1z C 24.1429 -16.0439
4 C1x C 26.4819 -17.4297
5 C1y C 21.7804 -17.3829
6 C1x C 22.9558 -19.4413
7 C1x C 22.9792 -15.3538
8 C1y C 25.3299 -15.3772
9 C1a C 24.1371 -14.6813
10 C1x C 26.4996 -16.0730
11 C8y C 20.5935 -18.0672
12 C1x C 21.7921 -16.0262
13 C1x C 21.7687 -20.1138
14 O1a O 25.3242 -14.0089
15 C8y C 20.5877 -19.4296
16 C8x C 19.4123 -17.3829
17 C8x C 19.4123 -20.1079
18 C8x C 18.2369 -18.0672
19 C8y C 18.2310 -19.4296
20 O7a O 17.0439 -20.1079
21 C7a C 15.8016 -19.3831
22 C1a C 14.5971 -20.0715
23 O6a O 15.8079 -17.9901
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 8 14 1 #Up
14 11 15 2
15 11 16 1
16 15 17 1
17 16 18 2
18 17 19 2
19 19 20 1
20 7 12 1
21 8 10 1
22 13 15 1
23 18 19 1
24 20 21 1
25 21 22 1
26 21 23 2
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