KEGG   DRUG: Estrogens, conjugatedHelp
Entry
D04070            Mixture   Drug                                   

Name
Estrogens, conjugated (JAN/USP);
Conjugated estrogens;
Premarin (TN)
Product
Component
Sodium estrone sulfate [DR:D00312], Sodium equilin sulfate, Sodium 17alfa-dihydroequilin sulfate
Class
Other
 DG01584  Estrogen receptor agonist
 DG01986  Estrogen
Enzyme substrate
 DG01633  CYP3A substrate
Transporter inhibitor
 DG02882  ABCB11 inhibitor
Remark
Therapeutic category: 2479
ATC code: G03CA57
Chemical structure group: DG00465
Product (DG00465): D04070<JP/US>
Product (mixture): D10579<US>
Efficacy
Replenisher (estrogen), Estrogen receptor agonist
Comment
Component of Cenestin (TN)
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Transporter inhibition: ABCB11 [HSA:8647]
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03C ESTROGENS
    G03CA Natural and semisynthetic estrogens, plain
     G03CA57 Conjugated estrogens
      D04070  Estrogens, conjugated (JAN/USP) <JP/US>
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
  Estrogens
   Estrogens, conjugated
    D04070  Estrogens, conjugated (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   247  Estrogen and progesterone preparations
    2479  Others
     D04070  Estrogens, conjugated (JAN/USP)
Drug classes of therapeutic agents [br08360.html]
 Endocrine and hormonal agents
  D04070
BRITE hierarchy
Other DBs
CAS: 12126-59-9
PubChem: 17398021
DrugBank: DB00286
LinkDB All DBs

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