KEGG   DRUG: Fostriecin sodium
Entry
D04262                      Drug                                   

Name
Fostriecin sodium (USAN)
Formula
C19H26O9P. Na
Exact mass
452.1212
Mol weight
452.3679
Structure
Efficacy
Antineoplastic
Target
PPP2C [HSA:5515 5516] [KO:K04382]
PPP4C [HSA:5531] [KO:K15423]
TOP2 [HSA:7153 7155] [KO:K03164]
  Pathway
hsa04151  PI3K-Akt signaling pathway
hsa04390  Hippo signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Phosphatases
    PPP2C
     D04262  Fostriecin sodium (USAN)
    PPP4C
     D04262  Fostriecin sodium (USAN)
  Isomerases (EC5)
   DNA topoisomerase
    TOP2
     D04262  Fostriecin sodium (USAN)
Other DBs
CAS: 87860-39-7
PubChem: 47206201
LigandBox: D04262
LinkDB
KCF data

ATOM        30
            1   C2x C    36.1200  -25.7600
            2   C2x C    36.1200  -24.3600
            3   C1x C    34.9300  -23.6600
            4   C1y C    33.6700  -24.3600
            5   O7x O    33.6700  -25.7600
            6   C7x C    34.9300  -26.4600
            7   O6a O    34.9300  -27.8600
            8   C2b C    32.4800  -23.6600
            9   C2b C    31.2900  -24.3600
            10  C1d C    30.1000  -23.6600
            11  C1c C    28.9100  -24.3600
            12  O1a O    31.0800  -22.6800
            13  C1a C    29.1200  -22.6800
            14  C1b C    27.7200  -23.6600
            15  O2b O    28.9100  -25.7600
            16  C1c C    26.5300  -24.3600
            17  C2b C    25.3400  -23.6600
            18  O1a O    26.5300  -25.7600
            19  C2b C    23.9400  -23.6600
            20  C2b C    22.7500  -24.3600
            21  C2b C    21.3500  -24.3600
            22  C2b C    20.1600  -23.6600
            23  C2b C    18.9000  -24.3600
            24  C1b C    17.7100  -23.6600
            25  O1a O    16.5200  -24.3600
            26  P1b P    30.1000  -26.4600
            27  O1c O    31.3600  -27.1600
            28  O1c O    29.4000  -27.6500 #-
            29  O1c O    30.8000  -25.2700
            30  Z   Na   26.6968  -27.5845 #+
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     6   7 2
            8     4   8 1 #Up
            9     8   9 2
            10    9  10 1
            11   10  11 1
            12   10  12 1 #Down
            13   10  13 1 #Up
            14   11  14 1
            15   11  15 1 #Down
            16   14  16 1
            17   16  17 1
            18   16  18 1 #Up
            19   17  19 2
            20   19  20 1
            21   20  21 2
            22   21  22 1
            23   22  23 2
            24   23  24 1
            25   24  25 1
            26   15  26 1
            27   26  27 1
            28   26  28 1
            29   26  29 2

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