Homo sapiens (human): 5516
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Entry
5516 CDS
T01001
Symbol
PPP2CB, PP2Abeta, PP2CB
Name
(RefSeq) protein phosphatase 2 catalytic subunit beta
KO
K04382
serine/threonine-protein phosphatase 2A catalytic subunit [EC:
3.1.3.16
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03015
mRNA surveillance pathway
hsa04071
Sphingolipid signaling pathway
hsa04110
Cell cycle
hsa04114
Oocyte meiosis
hsa04136
Autophagy - other
hsa04140
Autophagy - animal
hsa04151
PI3K-Akt signaling pathway
hsa04152
AMPK signaling pathway
hsa04261
Adrenergic signaling in cardiomyocytes
hsa04350
TGF-beta signaling pathway
hsa04390
Hippo signaling pathway
hsa04530
Tight junction
hsa04660
T cell receptor signaling pathway
hsa04728
Dopaminergic synapse
hsa04730
Long-term depression
hsa05142
Chagas disease
hsa05160
Hepatitis C
hsa05165
Human papillomavirus infection
Network
nt06166
Human papillomavirus (HPV)
nt06512
Chromosome cohesion and segregation
nt06530
PI3K signaling
nt06537
TCR/BCR signaling
Element
N00355
PP2A-AKT signaling pathway
N00356
HPV E7 to PP2A-AKT signaling patyway
N01485
Cohesin dissociation in prophase
N01497
Condensin loading
N01579
CD80/CD86-CTLA4-PP2A signaling pathway
Drug target
Fostriecin sodium:
D04262
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09122 Translation
03015 mRNA surveillance pathway
5516 (PPP2CB)
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
5516 (PPP2CB)
04390 Hippo signaling pathway
5516 (PPP2CB)
04071 Sphingolipid signaling pathway
5516 (PPP2CB)
04151 PI3K-Akt signaling pathway
5516 (PPP2CB)
04152 AMPK signaling pathway
5516 (PPP2CB)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
5516 (PPP2CB)
04136 Autophagy - other
5516 (PPP2CB)
09143 Cell growth and death
04110 Cell cycle
5516 (PPP2CB)
04114 Oocyte meiosis
5516 (PPP2CB)
09144 Cellular community - eukaryotes
04530 Tight junction
5516 (PPP2CB)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
5516 (PPP2CB)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
5516 (PPP2CB)
09156 Nervous system
04728 Dopaminergic synapse
5516 (PPP2CB)
04730 Long-term depression
5516 (PPP2CB)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
5516 (PPP2CB)
05165 Human papillomavirus infection
5516 (PPP2CB)
09174 Infectious disease: parasitic
05142 Chagas disease
5516 (PPP2CB)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsa01009
]
5516 (PPP2CB)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
5516 (PPP2CB)
04131 Membrane trafficking [BR:
hsa04131
]
5516 (PPP2CB)
03036 Chromosome and associated proteins [BR:
hsa03036
]
5516 (PPP2CB)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
5516 (PPP2CB)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.16 protein-serine/threonine phosphatase
5516 (PPP2CB)
Protein phosphatases and associated proteins [BR:
hsa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-2 (PP2A)
Catalytic subunits
5516 (PPP2CB)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Surveillance factors
Protein phosphatase 2A
5516 (PPP2CB)
Membrane trafficking [BR:
hsa04131
]
Autophagy
Other autophagy associated proteins
Others
5516 (PPP2CB)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Centromeric chromatin formation proteins
Other centromeric chromatin formation proteins
PP2A (protein phosphatase 2A)
5516 (PPP2CB)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
5516 (PPP2CB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Metallophos
STPPase_N
zf-TAZ
Glyco_hydro_65N
Motif
Other DBs
NCBI-GeneID:
5516
NCBI-ProteinID:
NP_001009552
OMIM:
176916
HGNC:
9300
Ensembl:
ENSG00000104695
Pharos:
P62714
(Tbio)
UniProt:
P62714
A0A140VJS0
LinkDB
All DBs
Position
8:complement(30785616..30812818)
Genome browser
AA seq
309 aa
AA seq
DB search
MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHG
QFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHES
RQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHI
RALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRA
HQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHV
TRRTPDYFL
NT seq
930 nt
NT seq
+upstream
nt +downstream
nt
atggacgacaaggcgttcaccaaggagctggaccagtgggtcgagcagctgaacgagtgt
aagcagctgaacgagaaccaagtgcggacgctgtgcgagaaggcaaaggaaattttaaca
aaagaatcaaatgtgcaagaggttcgttgccctgttactgtctgtggagatgtgcatggt
caatttcatgatcttatggaactctttagaattggtggaaaatcaccggatacaaactac
ttattcatgggtgactatgtagacagaggatattattcagtggagactgtgactcttctt
gtagcattaaaggtgcgttatccagaacgcattacaatattgagaggaaatcacgaaagc
cgacaaattacccaagtatatggcttttatgatgaatgtctgcgaaagtatgggaatgcc
aacgtttggaaatattttacagatctctttgattatcttccacttacagctttagtagat
ggacagatattctgcctccatggtggcctctctccatccatagacacactggatcatata
agagccctggatcgtttacaggaagttccacatgagggcccaatgtgtgatctgttatgg
tcagatccagatgatcgtggtggatggggtatttcaccacgtggtgctggctacacattt
ggacaagacatttctgaaacctttaaccatgccaatggtctcacactggtttctcgtgcc
caccagcttgtaatggagggatacaattggtgtcatgatcggaatgtggttaccattttc
agtgcacccaattactgttatcgttgtgggaaccaggctgctatcatggaattagatgac
actttaaaatattccttccttcaatttgacccagcgcctcgtcgtggtgagcctcatgtt
acacggcgcaccccagactacttcctataa
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