| Entry |
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| Name |
Idursulfase (USAN/INN);
Idursulfase (genetical recombination) (JAN);
Elaprase (TN)
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| Product |
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| Sequence |
SETQANSTTD ALNVLLIIVD DLRPSLGCYG DKLVRSPNID QLASHSLLFQ NAFAQQAVCA
PSRVSFLTGR RPDTTRLYDF NSYWRVHAGN FSTIPQYFKE NGYVTMSVGK VFHPGISSNH
TDDSPYSWSF PPYHPSSEKY ENTKTCRGPD GELHANLLCP VDVLDVPEGT LPDKQSTEQA
IQLLEKMKTS ASPFFLAVGY HKPHIPFRYP KEFQKLYPLE NITLAPDPEV PDGLPPVAYN
PWMDIRQRED VQALNISVPY GPIPVDFQRK IRQSYFASVS YLDTQVGRLL SALDDLQLAN
STIIAFTSDH GWALGEHGEW AKYSNFDVAT HVPLIFYVPG RTASLPEAGE KLFPYLDPFD
SASQLMEPGR QSMDLVELVS LFPTLAGLAG LQVPPRCPVP SFHVELCREG KNLLKHFRFR
DLEEDPYLPG NPRELIAYSQ YPRPSDIPQW NSDKPSLKDI KIMGYSIRTI DYRYTVWVGF
NPDEFLANFS DIHAGELYFV DSDPLQDHNM YNDSQGGDLF QLLMP |
|---|
| Type |
Peptide |
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| Remark |
| Therapeutic category: | 3959 |
|
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| Efficacy |
Enzyme replenisher (iduronate-2-sulfatase) |
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| Disease |
|
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| Comment |
iduronate-2-sulfatase [HSA: 3423] [KO: K01136] [EC: 3.1.6.13]
Treatment of Hunter Syndrome (enzyme that Lysosomal enzyme, degrades the glycosaminoglycans heparan sulfate and dermatan sulfate)
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A16 OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16A OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
A16AB Enzymes
A16AB09 Idursulfase
D04499 Idursulfase (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
Genetic or Enzyme Disorder: Replacement, Modifiers, Treatment
Idursulfase
D04499 Idursulfase (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
395 Enzyme preparations
3959 Others
D04499 Idursulfase (USAN/INN); Idursulfase (genetical recombination) (JAN)
New drug approvals in the USA [br08319.html]
New Molecular Entity and New Therapeutic Biological Product Approvals
D04499
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D04499
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D04499
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D04499
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| Other DBs |
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| LinkDB |
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