| Entry |
|
|---|
| Name |
Lotrafiban hydrochloride (USAN) |
|---|
| Formula |
C23H32N4O4. HCl
|
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| Exact mass |
464.2190
|
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| Mol weight |
464.98
|
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| Structure |
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| Class |
Blood modifier agent
DG01811 Fibrinogen receptor antagonist
|
|---|
| Efficacy |
Antithrombotic, Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist |
|---|
| Target |
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| Pathway |
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| Brite |
Drug groups [BR:br08330]
Blood modifier agent
DG01811 Fibrinogen receptor antagonist
D04785 Lotrafiban hydrochloride
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Cell adhesion molecules: other families
Integrins
ITGA2B/ITGB3
D04785 Lotrafiban hydrochloride (USAN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 32
1 C8y C 32.4265 -17.6314
2 N1x N 33.6829 -16.9334
3 C1y C 34.9392 -17.4918
4 C5x C 35.2882 -18.8877
5 C8y C 32.1473 -18.9575
6 N1y N 34.4506 -20.0045
7 C1x C 33.0547 -20.0045
8 C8x C 31.3796 -16.7240
9 C8x C 30.0534 -17.1428
10 C8y C 29.7742 -18.5388
11 C8x C 30.8212 -19.4461
12 C1a C 35.1486 -21.2608
13 O5x O 36.6841 -19.0971
14 C1b C 35.9861 -16.5844
15 C6a C 37.3123 -17.0730
16 O6a O 38.3592 -16.1657
17 O6a O 37.5915 -18.4690
18 C5a C 28.5642 -19.2430
19 N1y N 27.3184 -18.5357
20 O5a O 28.5741 -20.6310
21 C1x C 27.3184 -17.1357
22 C1x C 26.1060 -16.4357
23 C1y C 24.8935 -17.1357
24 C1x C 24.8935 -18.5357
25 C1x C 26.1060 -19.2357
26 C1y C 23.7071 -16.4507
27 C1x C 23.7072 -15.0502
28 C1x C 22.4947 -14.3502
29 N1x N 21.2823 -15.0502
30 C1x C 21.2823 -16.4507
31 C1x C 22.4947 -17.1507
32 X Cl 39.7479 -20.0092
BOND 34
1 3 4 1
2 1 5 1
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 1 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 5 11 2
13 6 12 1
14 4 13 2
15 3 14 1 #Up
16 14 15 1
17 15 16 1
18 15 17 2
19 10 18 1
20 18 19 1
21 18 20 2
22 19 21 1
23 21 22 1
24 22 23 1
25 23 24 1
26 24 25 1
27 19 25 1
28 23 26 1
29 26 27 1
30 27 28 1
31 28 29 1
32 29 30 1
33 30 31 1
34 26 31 1
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