KEGG   DRUG: Milodistim
Entry
D05036                      Drug                                   
Name
Milodistim (USAN/INN);
Pixykine (TN)
Formula
C1336H2116N362O410S13
Exact mass
30207.2225
Mol weight
30226.15
Sequence
APARSPSPST QPWEHVNAIQ EALRLLDLSR DTAAEMNEEV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQEGGG GSGGGGGSAP MTQTTPLKTS WVDCSNMIDE IITHLKQPPL PLLDFNNLNG
EDQDILMENN LRRPNLEAFN RAVKSLQDAS AIESILKNLL PCLPLATAAP TRHPIHIKDG
DWNEFRRKLT FYLKTLENAQ AQQTTLSLAI F
  Type
Peptide
Class
Immunological agent
 DG01753  Colony stimulating factor
Efficacy
Antineutropenic, Hematopoietic stimulant
Comment
A recombinant fusion protein (GM-CSF [HSA:1440] [KO:K05423] /IL3 [HSA:3562] [KO:K04736])
Target
CSF3R (GCSFR, CD114) [HSA:1441] [KO:K05061]
IL3RA (CD123) [HSA:3563] [KO:K04737]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Drug groups [BR:br08330]
 Immunological agent
  DG01753  Colony stimulating factor
   D05036  Milodistim
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interleukin receptors
    IL3RA (CD123)
     D05036  Milodistim (USAN/INN)
   CSF and other factor receptors
    CSF3R (GCSFR, CD114)
     D05036  Milodistim (USAN/INN)
Other DBs
CAS: 137463-76-4
PubChem: 47206763
LinkDB

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