KEGG T01001: 3562

Homo sapiens (human): 3562

Entry

3562              CDS       T01001

Symbol

IL3, IL-3, MCGF, MULTI-CSF

Name

(RefSeq) interleukin 3

K04736

interleukin 3

Organism

hsa Homo sapiens (human)

Pathway

hsa04060

Cytokine-cytokine receptor interaction

hsa04151

PI3K-Akt signaling pathway

hsa04210

Apoptosis

hsa04630

JAK-STAT signaling pathway

hsa04640

Hematopoietic cell lineage

hsa04664

Fc epsilon RI signaling pathway

hsa05200

Pathways in cancer

hsa05202

Transcriptional misregulation in cancer

hsa05221

Acute myeloid leukemia

hsa05310

Asthma

Network

nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06162  Hepatitis B virus (HBV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165  Epstein-Barr virus (EBV)
nt06219  JAK-STAT signaling (cancer)
nt06240  Transcription (cancer)
nt06263  Hepatocellular carcinoma
nt06266  Non-small cell lung cancer
nt06275  Acute myeloid leukemia
nt06276  Chronic myeloid leukemia
nt06518  JAK-STAT signaling

Element

N00053

Cytokine-Jak-STAT signaling pathway

N00116

Mutation-inactivated RUNX1 to transcription

N00118

TEL-AML1 fusion to transcriptional repression

N01804

IL3 family to Jak-STAT signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    3562 (IL3)
   04151 PI3K-Akt signaling pathway
    3562 (IL3)
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    3562 (IL3)
   04664 Fc epsilon RI signaling pathway
    3562 (IL3)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3562 (IL3)
   05202 Transcriptional misregulation in cancer
    3562 (IL3)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    3562 (IL3)
  09163 Immune disease
   05310 Asthma
    3562 (IL3)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:hsa04052]
    3562 (IL3)
   00536 Glycosaminoglycan binding proteins [BR:hsa00536]
    3562 (IL3)
Cytokines and neuropeptides [BR:hsa04052]
Cytokines
  Interleukins
   3562 (IL3)
Glycosaminoglycan binding proteins [BR:hsa00536]
Heparan sulfate / Heparin
  Cytokines
   3562 (IL3)

SSDB

Motif

Pfam:

IL3 Ldl_recept_b CdiA_C_tRNase

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

UniProt:

Structure

LinkDB

Position

5:132060655..132063204

AA seq 152 aa
MSRLPVLLLLQLLVRPGLQAPMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLN
GEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKD
GDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF

NT seq 459 nt +upstreamnt +downstreamnt
atgagccgcctgcccgtcctgctcctgctccaactcctggtccgccccggactccaagct
cccatgacccagacaacgcccttgaagacaagctgggttaactgctctaacatgatcgat
gaaattataacacacttaaagcagccacctttgcctttgctggacttcaacaacctcaat
ggggaagaccaagacattctgatggaaaataaccttcgaaggccaaacctggaggcattc
aacagggctgtcaagagtttacagaacgcatcagcaattgagagcattcttaaaaatctc
ctgccatgtctgcccctggccacggccgcacccacgcgacatccaatccatatcaaggac
ggtgactggaatgaattccggaggaaactgacgttctatctgaaaacccttgagaatgcg
caggctcaacagacgactttgagcctcgcgatcttttga

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