| Entry |
|
|---|
| Name |
Muzolimine (USAN/INN) |
|---|
| Formula |
C11H11Cl2N3O
|
|---|
| Exact mass |
271.0279
|
|---|
| Mol weight |
272.1305
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01748 Loop diuretic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antihypertensive, Diuretic |
|---|
| Comment |
loop diuretic
pyrazolone derivative
|
|---|
| Target |
|
|---|
| Interaction |
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| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03C HIGH-CEILING DIURETICS
C03CD Pyrazolone derivatives
C03CD01 Muzolimine
D05093 Muzolimine (USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01748 Loop diuretic
D05093 Muzolimine
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D05093 Muzolimine (USAN/INN)
SLC12A2 (NKCC1)
D05093 Muzolimine (USAN/INN)
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 17
1 C8y C 35.7458 -17.0425
2 C8y C 35.7458 -18.4456
3 C8x C 34.5531 -19.1472
4 C8x C 33.2903 -18.4456
5 C8y C 33.2903 -17.0425
6 C8x C 34.5531 -16.3409
7 X Cl 36.9384 -16.3409
8 X Cl 36.9384 -19.1472
9 C1c C 32.0976 -16.3409
10 N1y N 30.9050 -17.0425
11 C1a C 32.0976 -14.9378
12 C5x C 30.8583 -18.4562
13 C1x C 29.5658 -18.8861
14 C2y C 28.7336 -17.7807
15 N2x N 29.5204 -16.6317
16 N1a N 27.3395 -17.7997
17 O5x O 32.0073 -19.2431
BOND 18
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 2 8 1
9 5 9 1
10 9 10 1
11 9 11 1
12 10 12 1
13 12 13 1
14 13 14 1
15 14 15 2
16 10 15 1
17 14 16 1
18 12 17 2
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