KEGG   DRUG: Panitumumab
Entry
D05350                      Drug                                   
Name
Panitumumab (USAN/INN);
Panitumumab (genetical recombination) (JAN);
Vectibix (TN)
Product
Class
Antineoplastic
 DG01918  Tyrosine kinase inhibitor
  DG01917  Receptor tyrosine kinase inhibitor
   DG03162  EGFR inhibitor
Remark
Therapeutic category: 4291
ATC code: L01FE02
Product: D05350<JP/US>
Efficacy
Antineoplastic, Anti-epidermal growth factor receptor antibody
  Disease
Colorectal cancer (KRAS and NRAS wild type) [DS:H00020]
  Type
Monoclonal antibody
Target
EGFR [HSA:1956] [KO:K04361]
  Pathway
hsa04010  MAPK signaling pathway
hsa04012  ErbB signaling pathway
hsa05200  Pathways in cancer
Interaction
Structure map
map07045  Antineoplastics - protein kinase inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01F MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    L01FE EGFR (Epidermal Growth Factor Receptor) inhibitors
     L01FE02 Panitumumab
      D05350  Panitumumab (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Monoclonal Antibody/Antibody-Drug Conjugate
   Panitumumab
    D05350  Panitumumab (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D05350  Panitumumab (USAN/INN); Panitumumab (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Antineoplastic
  DG01918  Tyrosine kinase inhibitor
   DG01917  Receptor tyrosine kinase inhibitor
    DG03162  EGFR inhibitor
     D05350  Panitumumab
Drug classes [BR:br08332]
 Antineoplastic
  DG03162  EGFR inhibitor
   D05350  Panitumumab
Target-based classification of drugs [BR:br08310]
 Protein kinases
  Receptor tyrosine kinases (RTK)
   EGFR family
    EGFR
     D05350  Panitumumab (USAN/INN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D05350
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05350
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05350
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D05350
Pharmacogenomic biomarkers [br08341.html]
 Somatic variations in targeted cancer therapies
  D05350
Other DBs
CAS: 339177-26-3
PubChem: 47207035
NIKKAJI: J2.309.659E
LinkDB

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