KEGG   DRUG: Pimagedine hydrochlorideHelp
Entry
D05479                      Drug                                   

Name
Pimagedine hydrochloride (USAN);
Aminoguanidine hydrochloride
Product
Formula
CH6N4. HCl
Exact mass
110.0359
Mol weight
110.5461
Structure
Mol fileKCF fileDB search
Remark
Product: D05479<US>
Efficacy
Diamine oxidase inhbitor, Nitric oxide synthase inhibitor
  Disease
Eaton-Lambert syndrome [DS:H01596]
Comment
Inhibitor (advanced glycosylation end-product formation)
Treatment of diabetic nephropathy
Target
AOC1 (DAO) [HSA:26] [KO:K11182]
NOS [HSA:4842 4843 4846] [KO:K13240 K13241 K13242]
  Pathway
hsa04020  Calcium signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Amine oxidases
    AOC1 (DAO)
     D05479  Pimagedine hydrochloride (USAN) <US>
   Nitic oxide synthase
    NOS
     D05479  Pimagedine hydrochloride (USAN) <US>
BRITE hierarchy
Other DBs
CAS: 1937-19-5
PubChem: 47207148
ChEMBL: CHEMBL1256292
LigandBox: D05479
NIKKAJI: J220.058I
LinkDB All DBs
KCF data Show

ATOM        6
            1   N1a N    23.5489  -19.5003
            2   N1b N    22.3433  -18.8071
            3   C2c C    21.1262  -19.5003
            4   N1a N    19.9147  -18.8071
            5   N2a N    21.1262  -20.9038
            6   X   Cl   27.3332  -19.6130
BOND        4
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     3   5 2

» Japanese version   » Back

DBGET integrated database retrieval system