KEGG   DRUG: SibrafibanHelp
Entry
D05834                      Drug                                   

Name
Sibrafiban (USAN/INN)
Formula
C20H28N4O6
Exact mass
420.2009
Mol weight
420.4595
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01811  Fibrinogen receptor antagonist
Efficacy
Antithrombotic, Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist
Comment
Fibrinogen receptor antagonist
Target
ITGA2B/ITGB3 [HSA:3674 3690] [KO:K06476 K06493]
  Pathway
hsa04611  Platelet activation
hsa04640  Hematopoietic cell lineage
Brite
Target-based classification of drugs [BR:br08310]
 Cell surface molecules and ligands
  Cell adhesion molecules: other families
   Integrins
    ITGA2B/ITGB3
     D05834  Sibrafiban (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 172927-65-0
PubChem: 47207495
ChEMBL: CHEMBL435176
LigandBox: D05834
LinkDB All DBs
KCF data Show

ATOM        30
            1   C8x C    18.3400  -19.7400
            2   C8y C    18.3400  -18.3400
            3   C8x C    19.5300  -17.5700
            4   C8x C    20.7900  -18.3400
            5   C8y C    20.7900  -19.7400
            6   C8x C    19.5300  -20.4400
            7   C5a C    21.9800  -20.4400
            8   C2c C    17.0800  -17.5700
            9   N1a N    15.8900  -18.2700
            10  N2b N    17.0800  -16.1700
            11  N1b N    23.2400  -19.7400
            12  O5a O    21.9800  -21.8400
            13  C1c C    24.4300  -20.4400
            14  C5a C    25.6200  -19.7400
            15  C1a C    24.4300  -21.8400
            16  N1y N    26.8100  -20.4400
            17  O5a O    25.6200  -18.3400
            18  C1x C    28.0000  -19.7400
            19  C1x C    29.1900  -20.4400
            20  C1y C    29.1900  -21.8400
            21  C1x C    28.0000  -22.5400
            22  C1x C    26.8100  -21.8400
            23  O2a O    30.4500  -22.5400
            24  C1b C    31.6400  -21.8400
            25  C7a C    32.8300  -22.5400
            26  O7a O    34.0200  -21.8400
            27  C1b C    35.2800  -22.5400
            28  C1a C    36.4700  -21.8400
            29  O6a O    32.8300  -23.9400
            30  O1b O    15.8676  -15.4700
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     2   8 1
            9     8   9 1
            10    8  10 2
            11    7  11 1
            12    7  12 2
            13   11  13 1
            14   13  14 1
            15   13  15 1 #Down
            16   14  16 1
            17   14  17 2
            18   16  18 1
            19   18  19 1
            20   19  20 1
            21   20  21 1
            22   21  22 1
            23   16  22 1
            24   20  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   27  28 1
            30   25  29 2
            31   10  30 1

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