KEGG   DRUG: SufentanilHelp
Entry
D05938                      Drug                                   

Name
Sufentanil (USAN/INN)
Formula
C22H30N2O2S
Exact mass
386.2028
Mol weight
386.5508
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG02027  General anesthetics
  DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C08022
ATC code: N01AH03
Chemical structure group: DG00793
Product (DG00793): D00845<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH03 Sufentanil
      D05938  Sufentanil (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D05938  Sufentanil (USAN/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05938
BRITE hierarchy
Other DBs
CAS: 56030-54-7
PubChem: 47207596
ChEBI: 9316
ChEMBL: CHEMBL658
DrugBank: DB00708
LigandBox: D05938
NIKKAJI: J11.105H
LinkDB All DBs
KCF data Show

ATOM        27
            1   C8x C    17.1577  -27.3913
            2   C8x C    17.1577  -28.7920
            3   C8x C    18.3707  -29.4924
            4   C8x C    19.5838  -28.7920
            5   C8y C    19.5838  -27.3913
            6   C8x C    18.3707  -26.6909
            7   N1c N    20.8155  -26.6799
            8   C1z C    22.0213  -27.3760
            9   C1x C    22.0217  -28.7916
            10  C1x C    23.2350  -29.4916
            11  N1y N    24.4479  -28.7909
            12  C1x C    24.4474  -27.3752
            13  C1x C    23.2342  -26.6752
            14  C1b C    25.6567  -29.4883
            15  C1b C    26.8492  -28.7993
            16  C8y C    28.0393  -29.4859
            17  C8x C    28.4502  -30.8231
            18  C8x C    29.8542  -30.8454
            19  C8x C    30.3092  -29.5171
            20  S2x S    29.1866  -28.6738
            21  C5a C    20.8152  -25.2903
            22  O5a O    19.5903  -24.5833
            23  C1b C    22.0163  -24.5965
            24  C1a C    23.2069  -25.2837
            25  C1b C    20.7784  -28.0939
            26  O2a O    20.7784  -29.4947
            27  C1a C    19.5823  -30.1854
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   16  20 1
            23    7  21 1
            24   21  22 2
            25   21  23 1
            26   23  24 1
            27    8  25 1
            28   25  26 1
            29   26  27 1

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