KEGG   DRUG: Sufentanil
Entry
D05938                      Drug                                   
Name
Sufentanil (USAN/INN)
Formula
C22H30N2O2S
Exact mass
386.2028
Mol weight
386.5508
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
Same as: C08022
ATC code: N01AH03
Chemical structure group: DG00793
Product (DG00793): D00845<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH03 Sufentanil
      D05938  Sufentanil (USAN/INN)
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00793  Sufentanil
      D05938  Sufentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00793  Sufentanil
     D05938  Sufentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00793  Sufentanil
    D05938  Sufentanil
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D05938  Sufentanil (USAN/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05938
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00793  Sufentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00793  Sufentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00793  Sufentanil
Other DBs
CAS: 56030-54-7
PubChem: 47207596
ChEBI: 9316
LigandBox: D05938
NIKKAJI: J11.105H
LinkDB
KCF data

ATOM        27
            1   C8x C    17.1577  -27.3913
            2   C8x C    17.1577  -28.7920
            3   C8x C    18.3707  -29.4924
            4   C8x C    19.5838  -28.7920
            5   C8y C    19.5838  -27.3913
            6   C8x C    18.3707  -26.6909
            7   N1c N    20.8155  -26.6799
            8   C1z C    22.0213  -27.3760
            9   C1x C    22.0217  -28.7916
            10  C1x C    23.2350  -29.4916
            11  N1y N    24.4479  -28.7909
            12  C1x C    24.4474  -27.3752
            13  C1x C    23.2342  -26.6752
            14  C1b C    25.6567  -29.4883
            15  C1b C    26.8492  -28.7993
            16  C8y C    28.0393  -29.4859
            17  C8x C    28.4502  -30.8231
            18  C8x C    29.8542  -30.8454
            19  C8x C    30.3092  -29.5171
            20  S2x S    29.1866  -28.6738
            21  C5a C    20.8152  -25.2903
            22  O5a O    19.5903  -24.5833
            23  C1b C    22.0163  -24.5965
            24  C1a C    23.2069  -25.2837
            25  C1b C    20.7784  -28.0939
            26  O2a O    20.7784  -29.4947
            27  C1a C    19.5823  -30.1854
BOND        29
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   16  20 1
            23    7  21 1
            24   21  22 2
            25   21  23 1
            26   23  24 1
            27    8  25 1
            28   25  26 1
            29   26  27 1

» Japanese version   » Back

KEGG   DRUG: Sufentanil citrate
Entry
D00845                      Drug                                   
Name
Sufentanil citrate (USP);
Dsuvia (TN);
Sufenta (TN)
Product
  Generic
Formula
C22H30N2O2S. C6H8O7
Exact mass
578.2298
Mol weight
578.6743
Structure
Simcomp
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02026  Opioid anesthetics
 DG01564  Opioid receptor agonist
  DG01563  mu-Opioid receptor agonist
Analgesic
 DG01984  Opioid analgesics
Remark
ATC code: N01AH03
Chemical structure group: DG00793
Product (DG00793): D00845<US>
Efficacy
Analgesic (narcotic), Opioid receptor agonist
Comment
Phenylpiperidine derivative
Target
OPRM1 [HSA:4988] [KO:K04215]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Structure map
map07039  Opioid analgesics
map07224  Opioid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AH Opioid anesthetics
     N01AH03 Sufentanil
      D00845  Sufentanil citrate (USP) <US>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00793  Sufentanil
      D00845  Sufentanil citrate
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00793  Sufentanil
     D00845  Sufentanil citrate
 Analgesic
  DG01984  Opioid analgesics
   DG00793  Sufentanil
    D00845  Sufentanil citrate
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Opioid
    OPRM1
     D00845  Sufentanil citrate (USP) <US>
Drug groups [BR:br08330]
 Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02026  Opioid anesthetics
     DG00793  Sufentanil
  DG01564  Opioid receptor agonist
   DG01563  mu-Opioid receptor agonist
    DG00793  Sufentanil
 Analgesic
  DG01984  Opioid analgesics
   DG00793  Sufentanil
Other DBs
CAS: 60561-17-3
PubChem: 7847910
ChEBI: 9317
LigandBox: D00845
NIKKAJI: J269.155H
LinkDB
KCF data

ATOM        40
            1   C1d C    35.6633  -27.5656
            2   C1b C    34.4595  -28.2659
            3   C1b C    36.8796  -28.2598
            4   C6a C    36.3636  -26.3555
            5   O1a O    34.9630  -26.3495
            6   C6a C    33.2494  -27.5718
            7   C6a C    36.8796  -29.6540
            8   O6a O    35.6510  -25.1331
            9   O6a O    37.7581  -26.3555
            10  O6a O    32.0331  -28.2721
            11  O6a O    33.2432  -26.1713
            12  O6a O    38.0898  -30.3483
            13  O6a O    35.6573  -30.3483
            14  C8x C    17.1500  -27.4400
            15  C8x C    17.1500  -28.8400
            16  C8x C    18.3400  -29.5400
            17  C8x C    19.6000  -28.8400
            18  C8y C    19.6000  -27.4400
            19  C8x C    18.3400  -26.7400
            20  N1c N    20.7900  -26.7400
            21  C1z C    22.0500  -27.4400
            22  C1x C    22.0500  -28.8400
            23  C1x C    23.2400  -29.5400
            24  N1y N    24.4300  -28.8400
            25  C1x C    24.4300  -27.4400
            26  C1x C    23.2400  -26.7400
            27  C1b C    25.6900  -29.5400
            28  C1b C    26.8800  -28.8400
            29  C8y C    28.0700  -29.5400
            30  C8x C    28.4200  -30.8700
            31  C8x C    29.8200  -30.8700
            32  C8x C    30.3100  -29.6100
            33  S2x S    29.1900  -28.7700
            34  C5a C    20.7900  -25.3400
            35  O5a O    19.6000  -24.6400
            36  C1b C    22.0500  -24.6400
            37  C1a C    23.2400  -25.3400
            38  C1b C    20.7900  -28.1400
            39  O2a O    20.7900  -29.5400
            40  C1a C    19.6000  -30.2400
BOND        41
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     6  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 2
            13   14  15 2
            14   15  16 1
            15   16  17 2
            16   17  18 1
            17   18  19 2
            18   14  19 1
            19   18  20 1
            20   20  21 1
            21   21  22 1
            22   22  23 1
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   21  26 1
            27   24  27 1
            28   27  28 1
            29   28  29 1
            30   29  30 2
            31   30  31 1
            32   31  32 2
            33   32  33 1
            34   29  33 1
            35   20  34 1
            36   34  35 2
            37   34  36 1
            38   36  37 1
            39   21  38 1
            40   38  39 1
            41   39  40 1

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