KEGG   DRUG: TeriparatideHelp
Entry
D06078                      Drug                                   

Name
Teriparatide (USAN/INN);
Teriparatide (genetical recombination) (JAN);
Forteo (TN)
Product
Formula
C181H291N55O51S2
Exact mass
4115.1309
Mol weight
4117.7151
Sequence
Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu Asn
Ser Met Glu Arg Val Glu Trp Leu Arg Lys Lys Leu Gln Asp Val His
Asn Phe-OH
  Type
Peptide
Class
Other
 DG01661  Parathyroid hormone
Remark
Therapeutic category: 2439
ATC code: H05AA02
Chemical structure group: DG00512
Product (DG00512): D06078<JP/US> D03358<JP>
Efficacy
Antiresorptive, Osteoporosis agent, Parathyroid hormone receptor agonist
  Disease
Osteoporosis [DS:H01593]
Comment
Parathormone [CPD: C16051] analog
Target
PTH1R [HSA:5745] [KO:K04585]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04928  Parathyroid hormone synthesis, secretion and action
hsa04961  Endocrine and other factor-regulated calcium reabsorption
Interaction
Drug interaction
Structure map
map07047  Osteoporosis drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H05 CALCIUM HOMEOSTASIS
   H05A PARATHYROID HORMONES AND ANALOGUES
    H05AA Parathyroid hormones and analogues
     H05AA02 Teriparatide
      D06078  Teriparatide (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Metabolic Bone Disease Agents
  Teriparatide
   D06078  Teriparatide (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   243  Thyroid and parathyroid hormone preparations
    2439  Others
     D06078  Teriparatide (USAN/INN); Teriparatide (genetical recombination) (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Parathyroid hormone
    PTH1R
     D06078  Teriparatide (USAN/INN) <JP/US>
Drug classes of therapeutic agents [br08360.html]
 Osteoporosis drugs
  D06078
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D06078
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D06078
BRITE hierarchy
Other DBs
CAS: 52232-67-4
PubChem: 47207736
NIKKAJI: J2.191.211E
LinkDB All DBs

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