| Entry |
|
|---|
| Name |
Eptifibatide (INN);
Integrilin (TN) |
|---|
| Product |
|
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| Generic |
|
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| Formula |
C35H49N11O9S2
|
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| Exact mass |
831.3156
|
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| Mol weight |
831.97
|
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| Structure |
|
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01811 Fibrinogen receptor antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Platelet aggregation inhibitor, Glycoprotein IIb/IIIa receptor antagonist |
|---|
| Comment |
Treatment of Acute coronary syndrome
|
|---|
| Target |
|
|---|
| Pathway |
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| Interaction |
|
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| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC16 Eptifibatide
D06888 Eptifibatide (INN) <US>
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
D06888 Eptifibatide
DG01811 Fibrinogen receptor antagonist
D06888 Eptifibatide
Target-based classification of drugs [BR:br08310]
Cell surface molecules and ligands
Cell adhesion molecules: other families
Integrins
ITGA2B/ITGB3
D06888 Eptifibatide (INN) <US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D06888
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 57
1 C1b C 18.7088 -13.7108
2 C5a C 19.8059 -12.8468
3 N1b N 21.1717 -13.1584
4 C1c C 21.7738 -14.4120
5 C1b C 18.7088 -15.1203
6 C5a C 21.1726 -15.6797
7 N1b N 19.8059 -15.9914
8 C1b C 17.4960 -13.0106
9 S3a S 16.2830 -13.7108
10 N1b N 16.2830 -15.1203
11 C5a C 17.4960 -15.8206
12 S3a S 15.0702 -13.0106
13 C1b C 13.8574 -13.7108
14 C5a C 13.8574 -15.1203
15 C1c C 15.0702 -15.8206
16 C1c C 12.6445 -13.0106
17 N1b N 11.4317 -13.7108
18 C1c C 11.4317 -15.1203
19 N1b N 12.6445 -15.8206
20 C5a C 10.2188 -13.0106
21 C1y C 9.0059 -13.7108
22 N1y N 9.0059 -15.1203
23 C5a C 10.2188 -15.8206
24 C1x C 7.6655 -13.2753
25 C1x C 6.8370 -14.4156
26 C1x C 7.6655 -15.5559
27 O5a O 19.4918 -11.4542
28 O5a O 22.0432 -16.7652
29 O5a O 17.4959 -17.2273
30 O5a O 13.8573 -16.5271
31 O5a O 10.2187 -17.2274
32 O5a O 10.2188 -11.6254
33 C5a C 12.6449 -11.6258
34 C1b C 11.4318 -16.5270
35 O5a O 13.8817 -10.9118
36 N1a N 11.4561 -10.9388
37 C1b C 15.0703 -17.2273
38 C6a C 16.1138 -18.1470
39 O6a O 17.5084 -18.1449
40 O6a O 15.6221 -19.4512
41 C8y C 12.5155 -17.3949
42 C8y C 12.0831 -18.6924
43 C8y C 13.1918 -19.5005
44 N4x N 14.3028 -18.6958
45 C8x C 13.8809 -17.3903
46 C8x C 10.7241 -19.4142
47 C8x C 10.7347 -20.8147
48 C8x C 11.9280 -21.4916
49 C8x C 13.1355 -20.7822
50 C1b C 23.0144 -13.7651
51 C1b C 24.2287 -14.5371
52 C1b C 25.4597 -13.8950
53 C1b C 26.6501 -14.6525
54 N1b N 27.9233 -13.9887
55 C2c C 29.1261 -14.7540
56 N1a N 30.3635 -14.1090
57 N2a N 29.1348 -16.1754
BOND 60
1 3 4 1
2 4 6 1
3 2 3 1
4 5 7 1
5 1 2 1
6 6 7 1
7 1 8 1
8 8 9 1
9 10 11 1
10 5 11 1
11 9 12 1
12 12 13 1
13 14 15 1
14 10 15 1
15 13 16 1
16 16 17 1
17 18 19 1
18 14 19 1
19 17 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 18 23 1
24 21 24 1
25 24 25 1
26 25 26 1
27 22 26 1
28 2 27 2
29 6 28 2
30 11 29 2
31 14 30 2
32 23 31 2
33 20 32 2
34 16 33 1
35 18 34 1
36 33 35 2
37 33 36 1
38 15 37 1
39 37 38 1
40 38 39 2
41 38 40 1
42 34 41 1
43 41 42 1
44 42 43 1
45 43 44 1
46 44 45 1
47 41 45 2
48 42 46 2
49 46 47 1
50 47 48 2
51 48 49 1
52 43 49 2
53 4 50 1
54 50 51 1
55 51 52 1
56 52 53 1
57 53 54 1
58 54 55 1
59 55 56 1
60 55 57 2
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